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Tolun, Gökhan Dr.

Senior Lecturer

  • Senior Lecturer - University of Wollongong, NSW, Australia 2017 -
  • IRTA / CRTA - National Institutes of Health, MD, USA 2012 - 2017
  • Postdoctoral Research Associate - University of North Carolina at Chapel Hill, NC, USA 2008 - 2012

Overview

After receiving my Ph.D. and completing my postdoctoral training in the USA, I have joined UOW in December 2017 as an electron microscopy specialist, including cryo-EM.

Top Publications

    Year Title
    2016 Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina
    Published in   Proceedings of the National Academy of Sciences of USA
    2013 Details of ssDNA annealing revealed by an HSV-1 ICP8-ssDNA binary complex
    Published in   Nucleic Acids Research

Research Overview

  • Main main area of interest is studying bio-nano-machines carrying out processes involving nucleic acids, such as DNA recombination, replication, repair, and RNA transcription.

    My multi-disciplinary research group utilizes
    • Molecular imaging (Electron microscopy)
    • Structural biology (cryo-EM)
    • Biochemistry
    • Molecular Biology

    In addition to the state-of-the-art cryo-EM, we also use the classical EM techniques such as shadow-casting (i.e., metal shadowing) and negative staining.

Available as Research Supervisor

Available for Collaborative Projects

Selected Publications

Presentations

Available as Research Supervisor

Potential Supervision Topics

  • Revealing the molecular mechanistic details of single-strand DNA homologous recombination in double-strand DNA viruses via structural biology (cryo-EM), biochemistry and molecular imaging (electron microscopy)

    Studying the molecular mechanisms of bacterial DNA replication via structural biology (cryo-EM) and molecular imaging (electron microscopy)

    Understanding the structural details of bacterial transcription

Advisees

  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Understanding the Molecular Mechanisms of Single-strand Annealing Homologous DNA Recombination in Herpes Viruses, by cryo-EM Newing, Timothy
    Doctor of Philosophy Understanding the Molecular Mechanisms of Single-strand Annealing Homologous DNA Recombination in Bacteriophages, by cryo-EM Mantri, Bhanu

Awards And Honors

Teaching Overview

  • CHEM325 and BIOL215, UOW, School of Chemistry


    Teaching Assistant,     METU, Department of Biology, Ankara, Turkey

    1995-1996       Introduction to Biometry (Biostatistics) Computer Laboratory
    1996-1997       Molecular Genetics Laboratory for Biology Program
    1997-1998       Molecular Genetics Laboratory for Biology Program
    1998-1999       Molecular Genetics Laboratory for Mol. Biol. Program
    1998-1999       Microbiology Laboratory for Biology Program
    1999-2000       Molecular Genetics Laboratory for Biology Program
    1999-2000       Molecular Genetics Laboratory for Mol. Biol. Program

Web Of Science Researcher Id

  • D-1971-2012

Top Publications

    Year Title
    2016 Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina
    Published in   Proceedings of the National Academy of Sciences of USA
    2013 Details of ssDNA annealing revealed by an HSV-1 ICP8-ssDNA binary complex
    Published in   Nucleic Acids Research

Research Overview

  • Main main area of interest is studying bio-nano-machines carrying out processes involving nucleic acids, such as DNA recombination, replication, repair, and RNA transcription.

    My multi-disciplinary research group utilizes
    • Molecular imaging (Electron microscopy)
    • Structural biology (cryo-EM)
    • Biochemistry
    • Molecular Biology

    In addition to the state-of-the-art cryo-EM, we also use the classical EM techniques such as shadow-casting (i.e., metal shadowing) and negative staining.

Selected Publications

Presentations

Potential Supervision Topics

  • Revealing the molecular mechanistic details of single-strand DNA homologous recombination in double-strand DNA viruses via structural biology (cryo-EM), biochemistry and molecular imaging (electron microscopy)

    Studying the molecular mechanisms of bacterial DNA replication via structural biology (cryo-EM) and molecular imaging (electron microscopy)

    Understanding the structural details of bacterial transcription

Advisees

  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Understanding the Molecular Mechanisms of Single-strand Annealing Homologous DNA Recombination in Herpes Viruses, by cryo-EM Newing, Timothy
    Doctor of Philosophy Understanding the Molecular Mechanisms of Single-strand Annealing Homologous DNA Recombination in Bacteriophages, by cryo-EM Mantri, Bhanu

Awards And Honors

Teaching Overview

  • CHEM325 and BIOL215, UOW, School of Chemistry


    Teaching Assistant,     METU, Department of Biology, Ankara, Turkey

    1995-1996       Introduction to Biometry (Biostatistics) Computer Laboratory
    1996-1997       Molecular Genetics Laboratory for Biology Program
    1997-1998       Molecular Genetics Laboratory for Biology Program
    1998-1999       Molecular Genetics Laboratory for Mol. Biol. Program
    1998-1999       Microbiology Laboratory for Biology Program
    1999-2000       Molecular Genetics Laboratory for Biology Program
    1999-2000       Molecular Genetics Laboratory for Mol. Biol. Program

Web Of Science Researcher Id

  • D-1971-2012
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Visualisations

  Publication History