Fernandez-Enright, Francesca E.

Top Publications

Year	Title
2012	Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio Published in BMC Pharmacology
2012	Structural contributions of antipsychotic drugs to their therapeutic profiles and metabolic side effects Published in Journal of Neurochemistry

Selected Publications

Journal Article

Year	Title
2020	Electrophysiological correlates of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism Published In Scientific Reports
2019	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology
2018	Effects of common GRM5 genetic variants on cognition, hippocampal volume and mGluR5 protein levels in schizophrenia Published In Brain Imaging and Behavior: an international journal
2018	Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats Published In Neuronal Signaling
2018	Stress induced cortisol release and schizotypy Published In Psychoneuroendocrinology
2017	Alterations of ubiquitin related proteins in the pathology and development of schizophrenia: Evidence from human and animal studies Published In Journal of Psychiatric Research
2017	Effects of GRASP variation on memory in psychiatrically healthy individuals and cognitive dysfunction in schizophrenics Published In Gene Reports
2017	Shifting towards a model of mGluR5 dysregulation in schizophrenia: consequences for future schizophrenia treatment Published In Neuropharmacology
2016	Genetic consideration of schizotypal traits: a review Published In Frontiers in Psychology
2016	Lingo-1: a novel target in therapy for Alzheimer's disease? Published In Neural Regeneration Research
2016	Molecular evidence of synaptic pathology in CA1 in schizophrenia Published In Biological Psychiatry
2016	Molecular evidence of synaptic pathology in the CA1 region in schizophrenia Published In NPJ Schizophrenia
2016	Neurodevelopmental expression profile of dimeric and monomeric group 1 mGluRs: relevance to schizophrenia pathogenesis and treatment Published In Scientific Reports
2016	Possibility of a sex-specific role for a genetic variant in FRMPD4 in schizophrenia, but not cognitive function Published In NeuroReport
2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In International Journal of Neuropsychopharmacology
2015	A decade from discovery to therapy: Lingo-1, the dark horse in neurological and psychiatric disorders Published In Neuroscience and Biobehavioral Reviews
2015	Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation Published In Acta Neuropathologica
2015	Alterations of p75 neurotrophin receptor and Myelin transcription factor 1 in the hippocampus of perinatal phencyclidine treated rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Bardoxolone methyl prevents high-fat diet-induced alterations in prefrontal cortex signalling molecules involved in recognition memory Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Genetic Variation in GRM5 is Associated with Cognition, Hippocampal Volume and Schizophrenia Published In Neuropsychopharmacology
2015	Genetic variants in Nogo receptor signaling pathways may be associated with early life adversity in schizophrenia susceptibility Published In BBA Clinical
2015	Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia Published In Schizophrenia Research
2015	NMDA receptor antagonism by phencyclidine reduces NWASP and WAVE1 protein expression and reduces levels of myelination markers in the prefrontal cortex of rats Published In Journal of Pharmaceutics & Pharmacology
2014	Investigation of genetic variants in ubiquitin enzyme genes involved in the modulation of neurodevelopmental processes: a role in schizophrenia susceptibility? Published In Genetical Research
2014	Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics Published In Journal of Psychiatry and Neuroscience
2014	Novel implications of Lingo-1 and its signaling partners in schizophrenia Published In Translational Psychiatry
2014	Novel implications of lingo-1 signaling in the post-mortem schizophrenia brain Published In Biological Psychiatry
2013	Association of a GRIA3 gene polymorphism with migraine in an Australian case-control cohort Published In Headache
2013	In vivo pharmacological evaluations of novel olanzapine analogues in rats: a potential new avenue for the treatment of schizophrenia Published In PLoS One
2013	Short-term effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults Published In Metabolism: clinical and experimental
2012	Genetic modulation of the long-term effects of cannabis on brain structure, function and symptomatology Published In Schizophrenia Research
2012	Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio Published In BMC Pharmacology
2012	Structural contributions of antipsychotic drugs to their therapeutic profiles and metabolic side effects Published In Journal of Neurochemistry
2012	The dopamine b-hydroxylase 19 bp insertion/deletion polymorphism was associated with first-episode but not medicated chronic schizophrenia Published In Journal of Psychiatric Research
2012	Wip1 phosphatase positively modulates dendritic spine morphology and memory processes through the p38MAPK signaling pathway Published In Cell Adhesion and Migration
2011	Significant differences in gene expression of GABA receptors in peripheral blood leukocytes of migraineurs Published In Gene
2010	Genetics of menstrual migraine: the molecular evidence Published In Current Pain and Headache Reports
2010	Shorter telomere length in peripheral blood cells associated with migraine in women Published In Headache
2009	Association between migraine and a functional polymorphism at the DBH locus Published In Neurogenetics
2008	Investigation between the S377G3 GATA-4 polymorphism and migraine Published In The Open Neurology Journal
2008	Investigation of gamma-aminobutyric acid (GABA) A receptors genes and migraine susceptibility Published In BMC Medical Genetics
2007	A Pharmacogenomic Evaluation of Migraine Therapy Published In Expert Opinion on Pharmacotherapy
2007	Allelic variation investigation of the estrogen receptor within an Australian multiple sclerosis population Published In Journal of the Neurological Sciences
2007	Association analysis of chromosome 1 migraine candidate genes Published In BMC Medical Genetics
2007	Association study of a functional variant in intron 8 of the dopamine transporter gene and migraine susceptibility Published In European Journal of Neurology
2007	Gene expression studies in multiple sclerosis Published In Current Genomics
2007	Pharmacogenetics of migraine: genetic variants and their potential role in migraine therapy Published In Pharmacogenomics
2007	The search for migraine genes: an overview of current knowledge Published In Cellular and Molecular Life Sciences

Chapter

Year	Title
2007	The Genetics of Migraine Published In Migraine Disorders Research Trends

Conference Paper

Year	Title
2015	Association of a genetic variant in FRMPD4, encoding for the multi-scaffolding protein Preso1, with schizophrenia and cognition Published In Australian Society for Medical Research NSW Scientific Meeting
2015	Association of novel genetic variants in GRM5 with schizophrenia, cognition and hippocampal volume Published In Biological Psychiatry Australia Meeting
2015	Bardoxolone methyl: a potential therapeutic for the prevention of anti-psychotic drug-induced obesity? Published In Proceedings of 22nd Multidisciplinary ISBS International Neuroscience and Biological Psychiatry "Stress and Behavior" Conference
2015	The dark triad of personality traits, diurnal cortisol variations and sleep-wake cycles Published In Conference Abstract: ASP2015 - 25th Annual Conference of the Australasian Society for Psychophysiology
2014	Alterations of mGluR5 and mGluR5 signaling partners in schizophrenia Published In Abstracts for 2014 Society for Neuroscience Annual Meeting
2014	Effects of pharmacological blockade of Lingo - 1 signaling pathways in a phencyclidine rat model for schizophrenia Published In Abstracts for 2014 Society for Neuroscience Annual Meeting
2014	Evidence of mGluR5 dysregulation in schizophrenia Published In Australian Neuroscience Society 34th Annual Meeting
2014	Novel implications of Lingo-1 signaling in the prefrontal cortex and hippocampus of perinatal phencyclidine treated rats in a neurodevelopmental model of schizophrenia Published In Presentation Abstract of the Society of Biological Psychiatry 69th Annual Scientific Meeting
2014	Novel implications of Lingo-1 signaling in the prefrontal cortex of perinatal phencyclidine treated rats in a neurodevelopmental model of schizophrenia Published In Abstract of 9th FENS Forum of Neuroscience
2013	An analysis of metabotropic glutamate receptors 2/3 and 5 in schizophrenia, major depression and bipolar disorder from the stanley neuropathology consortium Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Expression of proteins within the nogo receptor complex are altered in the dorsolateral prefrontal cortex in schizophrenia Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Novel implications of Lingo-1 and its signalling partners in the Dorsolateral prefrontal cortex in schizophrenia Published In The 3rd Annual Biological Psychiatry Australia Scientific Meeting
2012	Proteogenomic analyses of Lingo-1 and the Nogo receptor in schizophrenia Published In The 32nd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants

Investigator On

Year	Title
2017 - 2024	Does Omega-3 Supplementation Attenuate Aggressive Behaviour: A Multi-Centre Randomised Controlled Trial of a Broadly Disseminable Strategy Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Partnership Projects
2012 - 2016	Schizophrenia: reversal of antipsychotic drug-induced obesity and its related metabolic disorders Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013 - 2014	Investigation of anti-Lingo-1 as an emergent actor in the therapy for schizophrenia Awarded by: Schizophrenia Research Institute Funding Scheme: Grant in Aid
2011	Vulnerability markers in the association between cannabis and schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2010 - 2011	Prevention and early diagnosis of Alzheimer's disease: New models of detection using gene expression profiling in a case-control elderly population in the Illawarra region Awarded by: IRT Research Foundation Funding Scheme: Grant
2010	Precellys 24 tissue homogenizer and digital microplate shaker Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2008	The Development vitam D model (DVD) as an animal model for schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant

Top Publications

Year	Title
2012	Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio Published in BMC Pharmacology
2012	Structural contributions of antipsychotic drugs to their therapeutic profiles and metabolic side effects Published in Journal of Neurochemistry

Selected Publications

Journal Article

Year	Title
2020	Electrophysiological correlates of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism Published In Scientific Reports
2019	Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression Published In Journal of Psychopharmacology
2018	Effects of common GRM5 genetic variants on cognition, hippocampal volume and mGluR5 protein levels in schizophrenia Published In Brain Imaging and Behavior: an international journal
2018	Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats Published In Neuronal Signaling
2018	Stress induced cortisol release and schizotypy Published In Psychoneuroendocrinology
2017	Alterations of ubiquitin related proteins in the pathology and development of schizophrenia: Evidence from human and animal studies Published In Journal of Psychiatric Research
2017	Effects of GRASP variation on memory in psychiatrically healthy individuals and cognitive dysfunction in schizophrenics Published In Gene Reports
2017	Shifting towards a model of mGluR5 dysregulation in schizophrenia: consequences for future schizophrenia treatment Published In Neuropharmacology
2016	Genetic consideration of schizotypal traits: a review Published In Frontiers in Psychology
2016	Lingo-1: a novel target in therapy for Alzheimer's disease? Published In Neural Regeneration Research
2016	Molecular evidence of synaptic pathology in CA1 in schizophrenia Published In Biological Psychiatry
2016	Molecular evidence of synaptic pathology in the CA1 region in schizophrenia Published In NPJ Schizophrenia
2016	Neurodevelopmental expression profile of dimeric and monomeric group 1 mGluRs: relevance to schizophrenia pathogenesis and treatment Published In Scientific Reports
2016	Possibility of a sex-specific role for a genetic variant in FRMPD4 in schizophrenia, but not cognitive function Published In NeuroReport
2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In International Journal of Neuropsychopharmacology
2015	A decade from discovery to therapy: Lingo-1, the dark horse in neurological and psychiatric disorders Published In Neuroscience and Biobehavioral Reviews
2015	Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation Published In Acta Neuropathologica
2015	Alterations of p75 neurotrophin receptor and Myelin transcription factor 1 in the hippocampus of perinatal phencyclidine treated rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Bardoxolone methyl prevents high-fat diet-induced alterations in prefrontal cortex signalling molecules involved in recognition memory Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Genetic Variation in GRM5 is Associated with Cognition, Hippocampal Volume and Schizophrenia Published In Neuropsychopharmacology
2015	Genetic variants in Nogo receptor signaling pathways may be associated with early life adversity in schizophrenia susceptibility Published In BBA Clinical
2015	Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia Published In Schizophrenia Research
2015	NMDA receptor antagonism by phencyclidine reduces NWASP and WAVE1 protein expression and reduces levels of myelination markers in the prefrontal cortex of rats Published In Journal of Pharmaceutics & Pharmacology
2014	Investigation of genetic variants in ubiquitin enzyme genes involved in the modulation of neurodevelopmental processes: a role in schizophrenia susceptibility? Published In Genetical Research
2014	Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics Published In Journal of Psychiatry and Neuroscience
2014	Novel implications of Lingo-1 and its signaling partners in schizophrenia Published In Translational Psychiatry
2014	Novel implications of lingo-1 signaling in the post-mortem schizophrenia brain Published In Biological Psychiatry
2013	Association of a GRIA3 gene polymorphism with migraine in an Australian case-control cohort Published In Headache
2013	In vivo pharmacological evaluations of novel olanzapine analogues in rats: a potential new avenue for the treatment of schizophrenia Published In PLoS One
2013	Short-term effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults Published In Metabolism: clinical and experimental
2012	Genetic modulation of the long-term effects of cannabis on brain structure, function and symptomatology Published In Schizophrenia Research
2012	Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio Published In BMC Pharmacology
2012	Structural contributions of antipsychotic drugs to their therapeutic profiles and metabolic side effects Published In Journal of Neurochemistry
2012	The dopamine b-hydroxylase 19 bp insertion/deletion polymorphism was associated with first-episode but not medicated chronic schizophrenia Published In Journal of Psychiatric Research
2012	Wip1 phosphatase positively modulates dendritic spine morphology and memory processes through the p38MAPK signaling pathway Published In Cell Adhesion and Migration
2011	Significant differences in gene expression of GABA receptors in peripheral blood leukocytes of migraineurs Published In Gene
2010	Genetics of menstrual migraine: the molecular evidence Published In Current Pain and Headache Reports
2010	Shorter telomere length in peripheral blood cells associated with migraine in women Published In Headache
2009	Association between migraine and a functional polymorphism at the DBH locus Published In Neurogenetics
2008	Investigation between the S377G3 GATA-4 polymorphism and migraine Published In The Open Neurology Journal
2008	Investigation of gamma-aminobutyric acid (GABA) A receptors genes and migraine susceptibility Published In BMC Medical Genetics
2007	A Pharmacogenomic Evaluation of Migraine Therapy Published In Expert Opinion on Pharmacotherapy
2007	Allelic variation investigation of the estrogen receptor within an Australian multiple sclerosis population Published In Journal of the Neurological Sciences
2007	Association analysis of chromosome 1 migraine candidate genes Published In BMC Medical Genetics
2007	Association study of a functional variant in intron 8 of the dopamine transporter gene and migraine susceptibility Published In European Journal of Neurology
2007	Gene expression studies in multiple sclerosis Published In Current Genomics
2007	Pharmacogenetics of migraine: genetic variants and their potential role in migraine therapy Published In Pharmacogenomics
2007	The search for migraine genes: an overview of current knowledge Published In Cellular and Molecular Life Sciences

Chapter

Year	Title
2007	The Genetics of Migraine Published In Migraine Disorders Research Trends

Conference Paper

Year	Title
2015	Association of a genetic variant in FRMPD4, encoding for the multi-scaffolding protein Preso1, with schizophrenia and cognition Published In Australian Society for Medical Research NSW Scientific Meeting
2015	Association of novel genetic variants in GRM5 with schizophrenia, cognition and hippocampal volume Published In Biological Psychiatry Australia Meeting
2015	Bardoxolone methyl: a potential therapeutic for the prevention of anti-psychotic drug-induced obesity? Published In Proceedings of 22nd Multidisciplinary ISBS International Neuroscience and Biological Psychiatry "Stress and Behavior" Conference
2015	The dark triad of personality traits, diurnal cortisol variations and sleep-wake cycles Published In Conference Abstract: ASP2015 - 25th Annual Conference of the Australasian Society for Psychophysiology
2014	Alterations of mGluR5 and mGluR5 signaling partners in schizophrenia Published In Abstracts for 2014 Society for Neuroscience Annual Meeting
2014	Effects of pharmacological blockade of Lingo - 1 signaling pathways in a phencyclidine rat model for schizophrenia Published In Abstracts for 2014 Society for Neuroscience Annual Meeting
2014	Evidence of mGluR5 dysregulation in schizophrenia Published In Australian Neuroscience Society 34th Annual Meeting
2014	Novel implications of Lingo-1 signaling in the prefrontal cortex and hippocampus of perinatal phencyclidine treated rats in a neurodevelopmental model of schizophrenia Published In Presentation Abstract of the Society of Biological Psychiatry 69th Annual Scientific Meeting
2014	Novel implications of Lingo-1 signaling in the prefrontal cortex of perinatal phencyclidine treated rats in a neurodevelopmental model of schizophrenia Published In Abstract of 9th FENS Forum of Neuroscience
2013	An analysis of metabotropic glutamate receptors 2/3 and 5 in schizophrenia, major depression and bipolar disorder from the stanley neuropathology consortium Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Expression of proteins within the nogo receptor complex are altered in the dorsolateral prefrontal cortex in schizophrenia Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Novel implications of Lingo-1 and its signalling partners in the Dorsolateral prefrontal cortex in schizophrenia Published In The 3rd Annual Biological Psychiatry Australia Scientific Meeting
2012	Proteogenomic analyses of Lingo-1 and the Nogo receptor in schizophrenia Published In The 32nd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants

Investigator On

Year	Title
2017 - 2024	Does Omega-3 Supplementation Attenuate Aggressive Behaviour: A Multi-Centre Randomised Controlled Trial of a Broadly Disseminable Strategy Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Partnership Projects
2012 - 2016	Schizophrenia: reversal of antipsychotic drug-induced obesity and its related metabolic disorders Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013 - 2014	Investigation of anti-Lingo-1 as an emergent actor in the therapy for schizophrenia Awarded by: Schizophrenia Research Institute Funding Scheme: Grant in Aid
2011	Vulnerability markers in the association between cannabis and schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2010 - 2011	Prevention and early diagnosis of Alzheimer's disease: New models of detection using gene expression profiling in a case-control elderly population in the Illawarra region Awarded by: IRT Research Foundation Funding Scheme: Grant
2010	Precellys 24 tissue homogenizer and digital microplate shaker Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2008	The Development vitam D model (DVD) as an animal model for schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant

Fernandez-Enright, Francesca E.

Faculty Member

Overview

Top Publications

Publications

Selected Publications

Journal Article

Chapter

Conference Paper

Funding

Investigator On

Overview

Top Publications

Publications

Selected Publications

Journal Article

Chapter

Conference Paper

Funding

Investigator On

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