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Tomaskovic-Crook, Eva Dr.

Senior Research Fellow

  • Affiliate Researcher - Illawarra Health and Medical Research Institute (IHMRI) 2014 -
  • Affiliate Researcher - Molecular Horizons 2018 -
  • Senior Research Scientist - Chris O'Brien Lifehouse 2021 -
  • Senior Research Fellow - Intelligent Polymer Research Institute 2022 -
  • Research Fellow, Synthetic Biosystems - ARC Centre of Excellence for Electromaterials Science 2014 - 2021

Overview


Dr Eva Tomaskovic-Crook is a Senior Research Fellow (2021-) at the Intelligent Polymer Research Institute (IPRI), Australian Institute for Innovative Materials, University of Wollongong, where she was until recently, Research Fellow (2014-2021) and Associate Theme Leader (2020-2021) with the Synthetic Biosystems Theme of the ARC Centre of Excellence for Electromaterials Science (ACES). She also holds an appointment as a Senior Research Scientist with Chris O’Brien Lifehouse Hospital’s Biomedical Innovation Hub (BMIH) (2021-). Eva completed her PhD in 2008 at the Ludwig Institute of Cancer Research, University of Melbourne in the field of cancer cell biology and targeted nanotherapeutics. As a Postdoctoral Fellow at A*STAR's Institute of Molecular and Cell Biology in Singapore, and St Vincent’s Institute in Melbourne, her research in cancer cell biology continued, to identify therapeutic targets of metastatic breast cancer using applied bioinformatic approaches. Prior to her PhD studies, Eva was a Senior Research Assistant in the field of Schizophrenia neurobiology and drug discovery at the Mental Health Research Institute in Melbourne, and the Clinical Brain Disorders Branch of the National Institute of Mental Health (NIMH) at the US National Institutes of Health (NIH) in Bethesda, USA.

Eva’s research brings together front-line technologies in human stem cells with cell instructive bio- and electro-materials for next generation tissue building. Her approach includes novel 3D-printing, stem-cell derived organoidogenesis, combined with electro-stimulation, particularly for neural tissue engineering and application, but also extending to cardiac tissue and tumour modelling. She has devised and demonstrated novel platforms to build and electrify human stem cells in two-dimensional (2D) and 3D to accelerate their development to specialised, mature and functionally interconnected cells and tissues, with increased responsivity to drug treatment. The platforms apply to both fundamental research and clinical translation: to model tissue development, function and dysfunction; to generate clinically relevant tissues for drug/toxicity testing and diagnostics; for tissue replacement and regenerative medicine; and, as models for medical device development, including advanced electroceuticals (electric pharmaceuticals), and to augment traditional pharmaceutical responsivity. Her work at Chris O’Brien Lifehouse in the Biomedical Innovation Hub is to enable the advancement of fundamental research to transform these innovations into clinical solutions including for cancer diagnostics, therapeutics, and regenerative medicine (tissue) therapy after cancer.

Top Publications


Research Overview


  • Dr Eva Tomaskovic-Crook is a Research Fellow within the Synthetic Biosystems theme of the ARC Centre of Excellence for Electromaterials Science (ACES) at the University of Wollongong (UOW). Eva completed her PhD in 2008 at the Ludwig Institute of Cancer Research, University of Melbourne in the field of cancer cell biology and targeted nanotherapeutics. As a Postdoctoral Fellow at A*STAR's Institute of Molecular and Cell Biology in Singapore, and St Vincent’s Institute in Melbourne, her research in cancer cell biology continued, to identify therapeutic targets of breast cancer using applied bioinformatic approaches. Prior to her PhD, Eva worked as a Senior Research Assistant for over 7 yrs in the field of Schizophrenia neurobiology and drug discovery at the Mental Health Research Institute in Melbourne, and the Clinical Brain Disorders Branch of the National Institute of Mental Health (NIMH) at the US National Institutes of Health (NIH) in Bethesda, USA.

    At UOW, working collaboratively with ACES CI, Associate Professor Jeremy Crook, Eva’s research brings together human stem cells with cell instructive bio- and electro-materials for next generation tissue building. Her interdisciplinary approach utilises cutting-edge technologies 3D-printing, stem-cell derived organoidogenesis, nanotechnology, and electro-stimulation; particularly for advanced human neural tissue engineering. Tissues are being developed and applied for drug/toxicity testing, medical device development, disease diagnostics, tissue replacement therapy, and regenerative medicine. In her role as a biomedical researcher, team-member and mentor at UOW, Eva is advancing knowledge and understanding in tissue development, disease modelling and diagnostics, whilst embracing the opportunity to train next-generation researchers, affirming UOW's position as a leader of learning and research.

Available as Research Supervisor

Selected Publications


Available as Research Supervisor

Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Modelling Ultrasound Mediated Neuromodulation: Towards Targeted Therapeutic Brain Stimulation
    Doctor of Philosophy Electro Stimulation of 3D Bioprinted Neural Tissues Warren, Danielle
    Doctor of Philosophy Direct Piezoelectricity for 3D Cardiac Tissue Engineering and Remodelling James, Emma
    Doctor of Philosophy Investigating the Therapeutic Effects of Electrical Stimulation on a 3D Human Organoid Glioblastoma Model Higginbottom, Sarah
    Doctor of Philosophy Electrifying 3D Human Neural Tissues for Enhanced Pharmacotherapy Jay, Sky
    Doctor of Philosophy Development of a Cell-Laden Electric Nerve Guidance Conduit Mohammadi, Mohammad

Education And Training


  • Doctor of Philosophy, Department of Surgery (RMH & WH) 2008

Web Of Science Researcher Id


  • C-9339-2016

Top Publications


Research Overview


  • Dr Eva Tomaskovic-Crook is a Research Fellow within the Synthetic Biosystems theme of the ARC Centre of Excellence for Electromaterials Science (ACES) at the University of Wollongong (UOW). Eva completed her PhD in 2008 at the Ludwig Institute of Cancer Research, University of Melbourne in the field of cancer cell biology and targeted nanotherapeutics. As a Postdoctoral Fellow at A*STAR's Institute of Molecular and Cell Biology in Singapore, and St Vincent’s Institute in Melbourne, her research in cancer cell biology continued, to identify therapeutic targets of breast cancer using applied bioinformatic approaches. Prior to her PhD, Eva worked as a Senior Research Assistant for over 7 yrs in the field of Schizophrenia neurobiology and drug discovery at the Mental Health Research Institute in Melbourne, and the Clinical Brain Disorders Branch of the National Institute of Mental Health (NIMH) at the US National Institutes of Health (NIH) in Bethesda, USA.

    At UOW, working collaboratively with ACES CI, Associate Professor Jeremy Crook, Eva’s research brings together human stem cells with cell instructive bio- and electro-materials for next generation tissue building. Her interdisciplinary approach utilises cutting-edge technologies 3D-printing, stem-cell derived organoidogenesis, nanotechnology, and electro-stimulation; particularly for advanced human neural tissue engineering. Tissues are being developed and applied for drug/toxicity testing, medical device development, disease diagnostics, tissue replacement therapy, and regenerative medicine. In her role as a biomedical researcher, team-member and mentor at UOW, Eva is advancing knowledge and understanding in tissue development, disease modelling and diagnostics, whilst embracing the opportunity to train next-generation researchers, affirming UOW's position as a leader of learning and research.

Selected Publications


Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Modelling Ultrasound Mediated Neuromodulation: Towards Targeted Therapeutic Brain Stimulation
    Doctor of Philosophy Electro Stimulation of 3D Bioprinted Neural Tissues Warren, Danielle
    Doctor of Philosophy Direct Piezoelectricity for 3D Cardiac Tissue Engineering and Remodelling James, Emma
    Doctor of Philosophy Investigating the Therapeutic Effects of Electrical Stimulation on a 3D Human Organoid Glioblastoma Model Higginbottom, Sarah
    Doctor of Philosophy Electrifying 3D Human Neural Tissues for Enhanced Pharmacotherapy Jay, Sky
    Doctor of Philosophy Development of a Cell-Laden Electric Nerve Guidance Conduit Mohammadi, Mohammad

Education And Training


  • Doctor of Philosophy, Department of Surgery (RMH & WH) 2008

Web Of Science Researcher Id


  • C-9339-2016
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