Brungs, Daniel

Selected Publications

• Journal Article

  Year	Title
  2022	A randomized, controlled, open-label, phase 2 study of cemiplimab ± RP1 in patients with advanced cutaneous squamous cell carcinoma (CERPASS). Published In Journal of Clinical Oncology
  2022	Antitumor activity of sunvozertinib in NSCLC patients with EGFR Exon20 insertion mutations after platinum and anti-PD(L)1 treatment failures. Published In Journal of Clinical Oncology
  2022	C-POST protocol update: A phase 3, randomized, double-blind study of adjuvant cemiplimab versus placebo post-surgery and radiation therapy (RT) in patients (pts) with high-risk cutaneous squamous cell carcinoma (CSCC). Published In Journal of Clinical Oncology
  2022	Clinical and molecular profile of young adults with early-onset colorectal cancer: Experience from four Australian tertiary centers Published In Asia-Pacific Journal of Clinical Oncology
  2022	EP08.02-029 Sunvozertinib in NSCLC Patients with EGFR Exon20 Insertion Mutations: Effect of Prior Treatment Published In Journal of Thoracic Oncology
  2022	Efficacy and safety of cosibelimab, an anti–PD-L1 antibody, in patients with metastatic cutaneous squamous cell carcinoma. Published In Journal of Clinical Oncology
  2022	Sunvozertinib, a Selective EGFR Inhibitor for Previously Treated Non-Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations. Published In Cancer discovery
  2021	1094TiP A randomized, controlled, open-label, phase II study of cemiplimab as a single agent and in combination with RP1 in patients with advanced cutaneous squamous cell carcinoma [CERPASS] Published In Annals of Oncology
  2021	547 CERPASS: A randomized, controlled, open-label, phase 2 study of cemiplimab ± RP1 in patients with advanced cutaneous squamous cell carcinoma Published In Journal for ImmunoTherapy of Cancer
  2021	Combination chemotherapy with NAB® -paclitaxel and capecitabine for patients with advanced biliary tract cancer (NAP-CAPABIL Pilot Study). Published In Asia-Pacific journal of clinical oncology
  2021	Experimental and clinical evidence supports the use of urokinase plasminogen activation system components as clinically relevant biomarkers in gastroesophageal adenocarcinoma Published In Cancers
  2021	Human TERT promoter mutations as a prognostic biomarker in glioma Published In Journal of Cancer Research and Clinical Oncology
  2021	OA15.02 Phase 1 Studies of DZD9008, an Oral Selective EGFR/HER2 Inhibitor in Advanced NSCLC with EGFR Exon20 Insertion Mutations Published In Journal of Thoracic Oncology
  2021	PD-L1 Detection on Circulating Melanoma Cells
  2021	Rectal cancer treatment and outcomes in elderly patients treated with curative intent Published In Molecular and Clinical Oncology
  2021	Single-Cell Analysis of BRAFV600E and NRASQ61R Mutation Status in Melanoma Cell Lines as Method Generation for Circulating Melanoma Cells
  2020	399 Cosibelimab, an anti-PD-L1 antibody: preliminary safety and efficacy results from a global, multicohort phase 1 clinical trial Published In Journal for ImmunoTherapy of Cancer
  2020	Central Venous Catheter Thrombosis in Cancer: A Multi-Centre Retrospective Study Investigating Risk Factors and Contemporary Trends in Management. Published In Clinical Medicine Insights. Oncology
  2020	Comparison of peripheral blood mononuclear cell isolation techniques and the impact of cryopreservation on human lymphocytes expressing CD39 and CD73 Published In Purinergic Signalling
  2020	Cosibelimab, an anti-PD-L1 antibody, in metastatic cutaneous squamous cell carcinoma (mCSCC): Preliminary safety and efficacy results from a phase I clinical trial Published In Annals of Oncology
  2020	Establishment of novel long-term cultures from EpCAM positive and negative circulating tumour cells from patients with metastatic gastroesophageal cancer Published In Scientific Reports
  2020	High body mass index is associated with an increased overall survival in rectal cancer Published In Journal of Gastrointestinal Oncology
  2020	Pancreatitis and Biliary Obstruction Secondary to Duodenal Metastasis from Rapidly Progressing Lung Adenocarcinoma Treated with Common Bile Duct Stenting Published In Case Reports in Oncology
  2020	Retrospective Evaluation of the Use of Pembrolizumab in Malignant Mesothelioma in a Real-World Australian Population. Published In JTO clinical and research reports
  2020	The role of liquid biopsies in detecting molecular tumor biomarkers in brain cancer patients Published In Cancers
  2019	Disseminated intravascular coagulation and melanoma: a novel case occurring in metastatic melanoma with BRAF and NRAS mutations and systematic review Published In MELANOMA RESEARCH
  2019	Expression of cancer stem cell markers is prognostic in metastatic gastroesophageal adenocarcinoma Published In Pathology
  2019	First-in-human phase I study of infusional and bolus schedules of Deflexifol, a novel 5-fluorouracil and leucovorin formulation, after failure of standard treatment Published In Asia Pacific Journal of Clinical Oncology
  2019	Immunomagnetic isolation of circulating melanoma cells and detection of PD-L1 status Published In PLoS ONE
  2019	Patterns of adjuvant therapy use and survival outcomes in patients with rectal cancer not receiving neoadjuvant therapy in an Australian cohort. Published In Journal of Clinical Oncology
  2019	Rectal cancer treatment and outcomes in elderly patients treated with curative intent. Published In Journal of Clinical Oncology
  2018	Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer Published In World Journal of Gastroenterology
  2018	NAP-CAPABIL: Pilot study of NAB-paclitaxel in combination with capecitabine as second line treatment of advanced biliary cancer. Published In Journal of Clinical Oncology
  2018	Safety and Efficacy of Oxaliplatin Doublet Adjuvant Chemotherapy in Elderly Patients With Stage III Colon Cancer Published In Clinical Colorectal Cancer
  2017	Deflexifol (a novel formulation of 5FU): Pharmacokinetics in a phase 1 trial in comparison to 5FU. Published In Journal of Clinical Oncology
  2017	Deflexifol (a novel formulation of 5FU): Phase 1 dose escalation study of infusional and bolus schedules after failure of standard treatment. Published In Journal of Clinical Oncology
  2017	Phase 1 study of infusional or bolus deflexifol (a novel formulation of 5FU, folinic acid, and cyclodextrin) after failure of standard treatment. Published In Journal of Clinical Oncology
  2017	Sidedness is prognostic in locoregional colon cancer: an analysis of 9509 Australian patients Published In BMC Cancer
  2017	The urokinase plasminogen activation system in gastroesophageal cancer: A systematic review and meta-analysis Published In Oncotarget
  2016	Gastric cancer stem cells: evidence, potential markers, and clinical implications Published In Journal of Gastroenterology
  2014	Anticancer activity of combination targeted therapy using cetuximab plus vemurafenib for refractory BRAF (V600E)-mutant metastatic colorectal carcinoma. Published In Current oncology (Toronto, Ont.)
  2014	Intermittent androgen deprivation is a rational standard-of-care treatment for all stages of progressive prostate cancer: results from a systematic review and meta-analysis. Published In Prostate cancer and prostatic diseases
  2013	Complete Radiologic Response of Bulky Cerebral Metastases From Newly Diagnosed HER2-Positive Breast Cancer to Upfront Trastuzumab-Based Chemotherapy. Published In World journal of oncology

• Conference Paper

  Year	Title
  2018	Cancer stem cell markers in metastatic gastroesophageal adenocarcinoma Published In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
  2018	Drug and radio sensitivity profile of a primary CTC cell line derived from a patient with metastatic neuroendocrine tumour of the distal oesophagus Published In ESMO Open
  2018	Impact of rural and remoteness on overall survival in Australian patients with stage I-III colorectal cancer Published In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
  2016	Adjuvant chemotherapy for stage III colorectal cancer in the elderly Published In ANNALS OF ONCOLOGY
  2016	BIOBANKING AT A REGIONAL TERTIARY HOSPITAL: AN INITIAL EXPERIENCE AND IDENTIFICATION OF BARRIERS TO PATIENT CONSENT Published In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
  2016	EXPRESSION OF UROKINASE PLASMINOGEN ACTIVATION SYSTEM IN PRIMARY GASTRO-ESOPHAGEAL ADENOCARCINOMA: A SYSTEMATIC REVIEW AND META-ANALYSIS Published In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY