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Hyland, Christopher J. T. Dr

Senior Lecturer

  • Centre for Medical and Molecular Bioscience
  • Faculty of Science, Medicine and Health
  • School of Chemistry

Top Publications


Research Overview


  • My group is interested in developing new transition metal-catalysed reactions for the synthesis of small organic molecules.

    We aim to develop tools for chemists to build complex molecules that may be used in new pharmaceuticals or materials.  There is a particular focus on developing reactions that are efficient and selective so as to reduce waste and energy consumption.  Through collaborations we also aim to harness synthetic chemistry to learn more about biological systems and develop potential new therapeutics.

    We also use metals to develop novel catalytic organometallics as potential pharmaceutical agents.

Available as Research Supervisor

Selected Publications


Investigator On


Available as Research Supervisor

Potential Supervision Topics


  • 1) Combined experimental and theoretical investigations into gold-catalysed reactions

    2) Developing novel metal-catalysed dearomatisation reactions to build bioactive heterocyclic skeletons

    3) Redox-active drugs for the treatment of cancer and neglected tropic diseases

Teaching Activities


  • CHEM358 Coordinator and Lecturer 2012 -

Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Gold(I)-Catalysed Reactions of Cyclopropenyl Carbinol Derivatives Drew, Melanie
    Doctor of Philosophy Sleeping Sickness and Functionalised Pyrrolidine Synthesis an organ copper Mediated Ring Opening of Azidoes Brown, Ronald
    Doctor of Philosophy Old Dye, New Tricks – Diversity-Oriented Synthesis of Heterocycles from Cascade Reactions of Indigo Butler, Nicholas
    Doctor of Philosophy Gold-catalysed reactions for the synthesis of medicinally important molecules. Thadkapally, Srinivas
    Doctor of Philosophy Enhanced Scope of the Borono-Mannich Reactions with Methylallenyl Boronate and Organometallic Catalysed Cyclisations Joyce, Liam
    Doctor of Philosophy Molecular Weight-Growth Chemistry of Aromatic Radicals in the Gas-Phase Kelly, Paddy
    Doctor of Philosophy Investigation into the Stereochemistry of Metal-Catalysed Reactions for the Synthesis of Medicinally Relevant Molecules. Bird, Melissa
    Doctor of Philosophy Development of chemical reactions for the synthesis of bioactive heterocycles Pham, Pham
    Doctor of Philosophy Development of a Catalytic Asymmetric Fluoro-Petasis Reaction to the Synthesis of Bioactive Fluorinated Heterocycles Chevis, Philip
    Doctor of Philosophy (Integrated) Synthesis of Novel Antimicrobials for Mulit-Drug Resistance Tuberculosis and Methicillin-Resistant Staphylococcus aureus (MRSA) Majed, Hiwa
    Master of Philosophy -SMAH Synthesis of Broussonetine Alkaloids using 3-alkoxy, 3-acyloxy or 3-trialkylsilyl allyl organ indium, zinc or boron reagents Alyamani, Asma

Outreach And Community Service Activities


  • CSIRO CSIRO Scientists in Schools Ambassador 2012 -

Education And Training


Top Publications


Research Overview


  • My group is interested in developing new transition metal-catalysed reactions for the synthesis of small organic molecules.

    We aim to develop tools for chemists to build complex molecules that may be used in new pharmaceuticals or materials.  There is a particular focus on developing reactions that are efficient and selective so as to reduce waste and energy consumption.  Through collaborations we also aim to harness synthetic chemistry to learn more about biological systems and develop potential new therapeutics.

    We also use metals to develop novel catalytic organometallics as potential pharmaceutical agents.

Selected Publications


Investigator On


Potential Supervision Topics


  • 1) Combined experimental and theoretical investigations into gold-catalysed reactions

    2) Developing novel metal-catalysed dearomatisation reactions to build bioactive heterocyclic skeletons

    3) Redox-active drugs for the treatment of cancer and neglected tropic diseases

Teaching Activities


  • CHEM358 Coordinator and Lecturer 2012 -

Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Gold(I)-Catalysed Reactions of Cyclopropenyl Carbinol Derivatives Drew, Melanie
    Doctor of Philosophy Sleeping Sickness and Functionalised Pyrrolidine Synthesis an organ copper Mediated Ring Opening of Azidoes Brown, Ronald
    Doctor of Philosophy Old Dye, New Tricks – Diversity-Oriented Synthesis of Heterocycles from Cascade Reactions of Indigo Butler, Nicholas
    Doctor of Philosophy Gold-catalysed reactions for the synthesis of medicinally important molecules. Thadkapally, Srinivas
    Doctor of Philosophy Enhanced Scope of the Borono-Mannich Reactions with Methylallenyl Boronate and Organometallic Catalysed Cyclisations Joyce, Liam
    Doctor of Philosophy Molecular Weight-Growth Chemistry of Aromatic Radicals in the Gas-Phase Kelly, Paddy
    Doctor of Philosophy Investigation into the Stereochemistry of Metal-Catalysed Reactions for the Synthesis of Medicinally Relevant Molecules. Bird, Melissa
    Doctor of Philosophy Development of chemical reactions for the synthesis of bioactive heterocycles Pham, Pham
    Doctor of Philosophy Development of a Catalytic Asymmetric Fluoro-Petasis Reaction to the Synthesis of Bioactive Fluorinated Heterocycles Chevis, Philip
    Doctor of Philosophy (Integrated) Synthesis of Novel Antimicrobials for Mulit-Drug Resistance Tuberculosis and Methicillin-Resistant Staphylococcus aureus (MRSA) Majed, Hiwa
    Master of Philosophy -SMAH Synthesis of Broussonetine Alkaloids using 3-alkoxy, 3-acyloxy or 3-trialkylsilyl allyl organ indium, zinc or boron reagents Alyamani, Asma

Outreach And Community Service Activities


  • CSIRO CSIRO Scientists in Schools Ambassador 2012 -

Education And Training


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