Deng, Chao

Research Areas

Available as Research Supervisor

Selected Publications

Journal Article

Year	Title
2019	Early antipsychotic exposure affects NMDA and GABAA receptor binding in the brains of juvenile rats Published In Psychiatry Research Volume 273 Pages 739 - 745 ISSN 0165-1781 Altmetric
2019	Modulation by chronic antipsychotic administration of PKA- and GSK3β-mediated pathways and the NMDA receptor in rat ventral midbrain Published In Psychopharmacology Volume Online First Pages 1 - 11 ISSN 0033-3158 Altmetric
2019	Simvastatin improves olanzapine-induced dyslipidemia in rats through inhibiting hepatic mTOR signaling pathway Published In Acta Pharmacologica Sinica Volume Online First Pages 1 - 9 ISSN 1671-4083 Altmetric
2019	Weight gain in Major Depressive Disorder: Linking appetite and disordered eating to leptin and ghrelin. Published In Psychiatry Research Volume Online First Pages 1 - 8 ISSN 0165-1781 Altmetric
2018	BDNF as a pharmacogenetic target for antipsychotic treatment of schizophrenia Published In Neuroscience Letters Volume Online First Pages 1 - 5 ISSN 0304-3940 Altmetric
2018	Chronic antipsychotic treatment differentially modulates protein kinase A- and glycogen synthase kinase 3 beta-dependent signaling pathways, N-methyl-D-aspartate receptor and γ-aminobutyric acid A receptors in nucleus accumbens of juvenile rats Published In Journal of Psychopharmacology Volume 32 Pages 1252 - 1263 ISSN 0269-8811 Altmetric
2018	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the adult serotonin receptors Published In Neuropsychiatric Disease and Treatment Volume 14 Pages 1569 - 1583 ISSN 1176-6328 Altmetric
2018	Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol Published In Psychiatry Research Volume 260 Pages 152 - 157 ISSN 0165-1781 Altmetric
2018	Problematic eating behaviours, changes in appetite, and weight gain in Major Depressive Disorder: The role of leptin Published In Journal of Affective Disorders Volume 240 Pages 137 - 145 ISSN 1573-2517 Altmetric
2018	The effects of antipsychotics on the density of cannabinoid receptors in selected brain regions of male and female adolescent juvenile rats Published In Psychiatry Research Volume 266 Pages 317 - 322 ISSN 0165-1781 Altmetric
2017	Molecular mechanisms of antipsychotic drug-induced diabetes Published In Frontiers in Neuroscience Volume 11 Pages 643-1 - 643-12 ISSN 1662-453X Altmetric
2017	Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats Published In Scientific Reports Volume 7 Pages 2762-1 - 2762-13 ISSN 2045-2322 Altmetric
2017	Time-dependent effects of olanzapine treatment on the expression of histidine decarboxylase, H1 and H3 receptor in the rat brain: The roles in olanzapine-induced obesity Published In Psychoneuroendocrinology Volume 85 Pages 190 - 199 ISSN 0306-4530 Altmetric
2016	Ameliorating antipsychotic-induced weight gain by betahistine: mechanisms and clinical implications Published In Pharmacological Research Volume 106 Pages 51 - 63 ISSN 1096-1186 Altmetric
2016	Aripiprazole and haloperidol activate GSK3β-dependent signalling pathway differentially in various brain regions of rats Published In International Journal of Molecular Sciences Volume 17 Pages 459-1 - 459-11 ISSN 1661-6596 Altmetric
2016	Aripiprazole increases the PKA signalling and expression of the GABA_A receptor and CREB1 in the nucleus accumbens of rats Published In Journal of Molecular Neuroscience Volume 59 Pages 36 - 47 ISSN 0895-8696 Altmetric
2016	Berberine alleviates olanzapine-induced adipogenesis via the AMPKα-SREBP pathway in 3T3-L1 cells Published In International Journal of Molecular Sciences Volume 17 Pages 1865-1 - 1865-12 ISSN 1661-6596 Altmetric
2016	Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA_A receptor expression and CREB1 activity in rats Published In Scientific Reports Volume 6 Pages 30040-1 - 30040-12 ISSN 2045-2322 Altmetric
2016	Early antipsychotic exposure affects serotonin and dopamine receptor binding density differently in selected brain loci of male and female juvenile rats Published In Pharmacological Reports Volume 68 Pages 1028 - 1035 ISSN 1734-1140 Altmetric
2016	Early antipsychotic treatment in childhood/adolescent period has long-term effects on depressive-like, anxiety-like and locomotor behaviours in adult rats Published In Journal of Psychopharmacology Volume 30 Pages 204 - 214 ISSN 0269-8811 Altmetric
2016	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the dopamine neurotransmitter system Published In International Journal of Molecular Sciences Volume 17 Pages 1944-1 - 1944-20 ISSN 1661-6596 Altmetric
2016	Interaction of dopamine D₂ and 5-HT_1A receptor partial agonism on antipsychotic efficacy Published In Journal of Clinical Psychopharmacology Volume 36 Pages 192 - 193 ISSN 0271-0749 Altmetric
2016	Modelling complex relationships between physiological and psychosocial factors in depression Published In International Journal of Psychophysiology Volume 108 Page p. 357 ISSN 0167-8760 Altmetric
2016	Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6-hydroxydopamine lesioned rat brains Published In Life Sciences Volume 155 Pages 123 - 132 ISSN 0024-3205 Altmetric
2016	The second-generation antipsychotic drugs induced dyslipidemia: a review of research and mechanisms Published In Zhongguo Yaoxue Zazhi Volume 51 Pages 172 - 176 Altmetric
2015	Acute effects of oral olanzapine treatment on the expression of fatty acid and cholesterol metabolism-related gene in rats Published In Life Sciences Volume 128 Pages 72 - 78 ISSN 0024-3205 Altmetric
2015	Betahistine co-treatment ameliorates dyslipidemia induced by chronic olanzapine treatment in rats through modulation of hepatic AMPKα-SREBP-1 and PPARα-dependent pathways Published In Pharmacological Research Volume 100 Pages 36 - 46 ISSN 1096-1186 Altmetric
2015	Chronic betahistine co-treatment reverses olanzapine's effects on dopamine D2 but not 5-HT2A/2C bindings in rat brains Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 56 Pages 75 - 80 ISSN 0278-5846 Altmetric
2015	Differential effects of short- and long-term antipsychotic treatment on the expression of neuregulin-1 and ErbB4 receptors in the rat brain Published In Psychiatry Research Volume 225 Pages 347 - 354 ISSN 0165-1781 Altmetric
2015	Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases Published In Endocrine Volume 49 Pages 307 - 323 ISSN 1355-008X Altmetric
2015	Risperidone-induced weight gain and reduced locomotor activity in juvenile female rats: the role of histaminergic and NPY pathways Published In Pharmacological Research Volume 95-96 Pages 20 - 26 ISSN 1096-1186 Altmetric
2015	Unique effects of acute aripiprazole treatment on the dopamine D2 receptor downstream cAMP-PKA and Akt-GSK3β signalling pathways in rats Published In PLoS One Volume 10 Pages e0132722-1 - e0132722-20 ISSN 1932-6203 Altmetric
2014	Alterations of NMDA receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats Published In International Journal of Neuroscience Volume 124 Pages 457 - 465 ISSN 0020-7454 Altmetric
2014	Betahistine ameliorates olanzapine-induced weight gain through modulation of histaminergic, NPY and AMPK pathways Published In Psychoneuroendocrinology Volume 48 Pages 77 - 86 ISSN 0306-4530 Altmetric
2014	Different effects of Bifeprunox, Aripiprazole, and Haloperidol on body weight gain, food and water intake, and locomotor activity in rats Published In Pharmacology, Biochemistry and Behavior Volume 124 Pages 167 - 173 ISSN 1873-5177 Altmetric
2014	Effects of olanzapine on the elevation of macrophage infiltration and pro-inflammatory cytokine expression in female rats Published In Journal of Psychopharmacology Volume 28 Pages 1161 - 1169 ISSN 0269-8811 Altmetric
2014	Hypothalamic ghrelin signalling mediates olanzapine-induced hyperphagia and weight gain in female rats Published In International Journal of Neuropsychopharmacology Volume 17 Pages 807 - 818 ISSN 1461-1457 Altmetric
2014	Hypothalamic histamine H1 receptor-AMPK signaling time-dependently mediates olanzapine-induced hyperphagia and weight gain in female rats Published In Psychoneuroendocrinology Volume 42 Pages 153 - 164 ISSN 0306-4530 Altmetric
2014	Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics Published In Journal of Psychiatry and Neuroscience Volume 39 Pages 407 - 416 ISSN 0702-8466 Altmetric
2014	Olanzapine reduced brown adipose tissue thermogenesis and locomotor activity in female rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 51 Pages 172 - 180 ISSN 0278-5846 Altmetric
2014	Olanzapine-activated AMPK signaling in the dorsal vagal complex is attenuated by histamine H1 receptor agonist in female rats Published In Endocrinology Volume 155 Pages 4895 - 4904 ISSN 0013-7227 Altmetric
2014	Preventing olanzapine-induced weight gain using betahistine: a study in a rat model with chronic olanzapine treatment Published In PLoS One Volume 9 Pages e104160-1 - e104160-11 ISSN 1932-6203 Altmetric
2014	Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: the association with improvements in long-term memory Published In Neuroscience Volume 267 Pages 57 - 66 ISSN 0306-4522 Altmetric
2013	Effects of antipsychotic medications on appetite, weight, and insulin resistance Published In Endocrinology and Metabolism Clinics of North America Volume 42 Pages 545 - 563 ISSN 0889-8529 Altmetric
2013	Effects of olanzapine and betahistine co-treatment on serotonin transporter, 5-HT2A and dopamine D2 receptor binding density Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 47 Pages 62 - 68 ISSN 0278-5846 Altmetric
2013	Mapping the pathophysiology of schizophrenia: interactions between multiple cellular pathways Published In Frontiers in Cellular Neuroscience Volume 7 Pages 238-1 - 238-2 ISSN 1662-5102 Altmetric
2013	Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment Published In Schizophrenia Research Volume 146 Pages 170 - 176 ISSN 0920-9964 Altmetric
2013	Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway Published In Psychopharmacology Volume 226 Pages 201 - 215 ISSN 0033-3158 Altmetric
2013	Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor Published In CNS Drugs Volume 27 Pages 1069 - 1080 ISSN 1172-7047 Altmetric
2013	The association of antidepressant medication and body weight gain Published In Online Journal of Health and Allied Sciences Volume 12 Pages 1 - 9
2013	The role of ghrelin signalling in second-generation antipsychotic-induced weight gain Published In Psychoneuroendocrinology Volume 38 Pages 2423 - 2438 ISSN 0306-4530 Altmetric
2013	The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain Published In CNS Drugs Volume 27 Pages 423 - 434 ISSN 1172-7047 Altmetric
2012	Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain Published In PLoS One Volume 7 Pages e33548 - 1 - e33548 - 12 ISSN 1932-6203 Altmetric
2012	Are there different neural mechanisms responsible for three stages of weight gain development in anti-psychotic therapy: Temporally based hypothesis Published In Asian Journal of Psychiatry Volume 5 Pages 315 - 318 ISSN 1876-2018 Altmetric
2012	Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring Published In Psychopharmacology Volume 220 Pages 455 - 463 ISSN 0033-3158 Altmetric
2012	Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels Published In European Neuropsychopharmacology Volume 22 Pages 364 - 373 ISSN 0924-977X Altmetric
2012	Reducing olanzapine-induced weight gain side-effect by using betahistine: a study in the rat model Published In Journal of Psychopharmacology Volume 26 Pages 1271 - 1279 ISSN 0269-8811 Altmetric
2011	Antipsychotic treatment and neuregulin 1 -ErbB4 signalling in schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 35 Pages 924 - 930 ISSN 0278-5846 Altmetric
2011	Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats Published In Behavioural Brain Research Volume 217 Pages 337 - 346 ISSN 0166-4328 Altmetric
2011	Potential control of risperidone-related cognitive deficits by adjunctive aripiprazole treatment Published In Journal of Clinical Psychopharmacology Volume 31 Pages 135 - 136 ISSN 0271-0749 Altmetric
2011	Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses Published In PLoS One Volume 6 Pages e20945 - e20945 ISSN 1932-6203 Altmetric
2011	Statins: multiple neuroprotective mechanisms in neurodegenerative diseases Published In Experimental Neurology Volume 230 Pages 27 - 34 ISSN 0014-4886 Altmetric
2010	Alterations in 5-HT2A receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats Published In Synapse (New York) Volume 64 Pages 224 - 230 ISSN 0887-4476 Altmetric
2010	Effects of antipsychotic drugs on muscarinic M1 receptors in the rat brain Published In Australian and New Zealand Journal of Psychiatry Volume 44 Page p. A51 ISSN 1440-1614
2010	Effects of simvastatin and 6-hydroxydopamine on histaminergic H1 receptor binding density in rat brains Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 34 Pages 1419 - 1425 ISSN 0278-5846 Altmetric
2010	Effects of typical and atypical antipsychotics on the expressions of neuregulin 1 and ERBB4 receptors Published In Australian and New Zealand Journal of Psychiatry Volume 44 Pages A49 - A50 ISSN 1440-1614
2010	Molecular cloning and characterization of the global regulator LaeA in Penicillium citrinum Published In Biotechnology Letters Volume 32 Pages 1733 - 1737 ISSN 0141-5492 Altmetric
2010	Olanzapine decreases POMC MRNA expression and M3 receptors binding density in the hypothalamus and brainstem: pathway for weight gain side-effect? Published In Australian and New Zealand Journal of Psychiatry Volume 44 Page p. A55 ISSN 1440-1614
2010	Olanzapine decreases cannabinoid CB1 receptors in the hypothalamus and brainstem, possibly through muscarinic M3 receptor antagonism Published In International Journal of Neuropsychopharmacology Volume 13 Pages 111 - 112 ISSN 1461-1457 Altmetric
2010	Potential control of antipsychotic-induced hyperprolactinemia and obesity in children and adolescents by aripiprazole Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 34 Pages 1157 - 1158 ISSN 0278-5846 Altmetric
2010	Reduce the olanzapine-induced body weight gain with histamine H1 receptor agonist betahistine in rats Published In International Journal of Neuropsychopharmacology Volume 13 Page p. 99 ISSN 1461-1457 Altmetric
2010	Sensitivity of the female rat to olanzapine-induced weight gain - far from the clinic? Published In Schizophrenia Research Volume 116 Pages 299 - 300 ISSN 0920-9964 Altmetric
2010	The role of histaminergic H1 and H3 receptors in food intake:-A mechanism fo atypical antipsychotic-induced weight gain? Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 34 Pages 1 - 4 ISSN 0278-5846 Altmetric
2010	What is the mechanism for aripiprazole's effect on reducing olanzapine-associated obesity? Published In Journal of Clinical Psychopharmacology Volume 30 Pages 480 - 481 ISSN 0271-0749 Altmetric
2009	Aripiprazole differentially affects mesolimbic and nigrostriatal dopaminergic transmission: implications for long-term drug efficacy and low extrapyramidal side-effects Published In International Journal of Neuropsychopharmacology Volume 12 Pages 941 - 952 ISSN 1461-1457 Altmetric
2009	Decreased density of serotonin 2A receptors in the superior temporal gyrus in schizophrenia - a postmortem study Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 33 Pages 867 - 871 ISSN 0278-5846 Altmetric
2009	Excitatory and inhibitory neurotransmission is chronically altered following perinatal NMDA receptor blockade Published In European Neuropsychopharmacology Volume 19 Pages 256 - 265 ISSN 0924-977X Altmetric
2009	High dose of simvastatin induces hyperlocomotive and anxiolytic-like activities: the association with the up-regulation of NMDA receptor binding in the rat brain Published In Experimental Neurology Volume 216 Pages 132 - 138 ISSN 0014-4886 Altmetric
2009	Obese reversal by a chronic energy restricted diet leaves an increased Arc NPY/AgRP, but no alteration in POMC/CART, mRNA expression in diet-induced obese mice Published In Behavioural Brain Research Volume 205 Pages 50 - 56 ISSN 0166-4328 Altmetric
2009	Perinatal PCP treatment alters the developmental expression of prefrontal and hippocampal muscarinic receptors Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 33 Pages 37 - 40 ISSN 0278-5846 Altmetric
2009	Serotonin 2A receptor and its association with the pathology of schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 33 Pages 1585 - 1586 ISSN 0278-5846 Altmetric
2009	The effects of antipsychotic drugs administration on 5-HT1A receptor expression in the limbic system of the rat brain Published In Neuroscience Volume 164 Pages 1754 - 1763 ISSN 0306-4522 Altmetric
2008	Altered dopamine receptor and dopamine transporter binding and tyrosine hydroxylase mRNA expression following perinatal NMDA receptor blockade Published In Neurochemical Research Volume 33 Pages 1224 - 1231 ISSN 0364-3190 Altmetric
2008	Effects of antipsychotic medication on muscarinic M1 receptor mRNA expression in the rat brain Published In Journal of Neuroscience Research Volume 86 Pages 457 - 464 ISSN 0360-4012 Altmetric
2008	Perinatal NMDA receptor blockade alters D2, NMDA and M1/M4 receptors in later life: implications for pathological processes of schizophrenia Published In Schizophrenia Research Volume 102 Page p. 68 ISSN 0920-9964
2008	Perinatal administration of PCP alters adult behaviour in female Sprague-Dawley rats Published In Behavioural Brain Research Volume 188 Pages 416 - 419 ISSN 0166-4328 Altmetric
2008	Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression Published In Psychoneuroendocrinology Volume 33 Pages 569 - 580 ISSN 0306-4530 Altmetric
2008	The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: Implications for olanzapine-induced weight gain Published In International Journal of Neuropsychopharmacology Volume 11 Pages 827 - 835 ISSN 1461-1457 Altmetric
2008	Ventromedial hypothalamic NPY Y2 receptor in the maintenance of body weight in diet-induced obesity in mice Published In Neurochemical Research Volume 33 Pages 1881 - 1888 ISSN 0364-3190 Altmetric
2007	A rodent model of NMDA receptor hypofunction for the study of schizophrenia Published In Neuroscience Bulletin Volume 23 Pages 81 - 81 ISSN 1673-7067
2007	A static handgrip method for distal quantitative sweat measurements Published In Neuroscience Letters Volume 421 Pages 229 - 233 ISSN 0304-3940 Altmetric
2007	AM 251 and beta-Funaltrexamine reduce fat intake in a fat-preferring strain of mouse Published In Behavioural Brain Research Volume 181 Pages 153 - 157 ISSN 0166-4328 Altmetric
2007	Decreased plasma peptide YY accompanied by elevated peptide YY and Y2 receptor binding densities in the medulla oblongata of diet-induced obese mice Published In Endocrinology Volume 148 Pages 4704 - 4710 ISSN 0013-7227 Altmetric
2007	Dose-dependent effects of atypical antipsychotic drug olanzapine on weight gain and cholecystokinin levels in rats Published In Neuroscience Bulletin Volume 23 Pages 352 - 352 ISSN 1673-7067
2007	Histamine H1 mRNA expression is decreased in the rat hypothalamus following olanzapine treatment Published In Schizophrenia Bulletin Volume 33 Page p. 317 ISSN 0586-7614
2007	NMDA receptor hypofunction during early brain development: relevance to schizophrenia Published In Schizophrenia Bulletin Volume 33 Page p. 317 ISSN 0586-7614
2007	No changes in cannabinoid CB1 receptor binding density in the superior temporal gyrus in schizophrenia Published In Schizophrenia Bulletin Volume 33 Pages 308 - 309 ISSN 0586-7614
2007	No changes in densities of cannabinoid receptors in the superior temporal gyrus in schizophrenia Published In Neuroscience Bulletin Volume 23 Pages 341 - 347 ISSN 1673-7067 Altmetric
2007	Olanzapine treatment decreases the density of muscarinic M2 receptors in the dorsal vagal complex of rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 31 Pages 915 - 920 ISSN 0278-5846 Altmetric

Conference Paper

Year	Title
2017	Relationships of hormone levels with hunger, weight gain and problematic eating behaviours in Major Depressive Disorder Published In Frontiers in Human Neuroscience Abstract: ASP2017 27th Annual Meeting for the Australasian Society for Psychophysiology Pages 1 - 1 Altmetric
2013	An analysis of metabotropic glutamate receptors 2/3 and 5 in schizophrenia, major depression and bipolar disorder from the stanley neuropathology consortium Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 49 - 49
2013	Binding affinity of aripiprazole to the dopamine D2 receptor in different regions of the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 115 - 115
2013	Central administration of histamine H1 receptor agonist, fMPH, blocks olanzapineinduced activation of ampk-cpt1 signaling in the dorsal vagal complex in rats Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 120 - 120
2013	Effects of chronic antipsychotic treatment on dopamine synthesis Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 115 - 115
2013	Long term effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 171 - 171
2013	Time-dependent ghrelinergic signaling and hyperphagia induced by olanzapine Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 48 - 48
2012	Differential effects of aripiprazole and haloperidol on dopamine markers in the arcuate nucleus and prolactin levels in male rats Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology Pages 60 - 60 Altmetric
2012	Effects of dopamine D2 receptor partial agonist bifeprunox on body weight gain, food and water intake in male rats Published In Australian Neuroscience Society 32nd Annual meeting Pages 150 - 150
2012	Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain Published In ANS 2012: Australian Neuroscience Society 32nd Annual meeting Page p. 97
2012	MGluR5 and NMDA receptor density are reduced in the dorsolateral prefrontal cortex of schizoaffective but not schizophrenia patients Published In Society of Biological Psychiatry 67th Annual Meeting
2012	Metabotropic glutamate receptor subtype 5 is reduced in schizophrenia subjects with comorbid major depression and unchanged following antipsychotic drug treatment Published In Australian Neuroscience Society 32nd Annual meeting Pages 95 - 95
2012	Olanzapine treatment and time-dependent changes of hypothalamic AMPK-ACC-CPT1 signalling, food intake and body weight in rats Published In ANS 2012: Australian Neuroscience Society 32nd Annual meeting Pages 148 - 148
2012	Preventing and treating olanzapine-induced obesity with betahistine: a chronic animal model study Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology Pages 56 - 56 Altmetric
2012	Time-dependant alterations of hypothalamic energy regulatory network by olanzapine in rats Published In Australian Neuroscience Society 32nd Annual meeting Pages 150 - 150
2011	Aripiprazole selectively affects AKT/GSK protein expression in the nucleus accumbens and caudate putamen Published In 31st Annual Meeting of the Australian Neuroscience Society Pages 54 - 54
2011	Histamine H1 receptor agonist and control of olanzapine-induced obesity Published In 31st Annual Meeting of the Australian Neuroscience Society Pages 126 - 126
2011	Neuroendocrinological regulation of insulin dysfunction induced by olanzapine Published In 31st Annual Meeting of the Australian Neuroscience Society Pages 54 - 54
2010	An age difference in mu opioid receptor binding density in the human putamen but no changes in schizophrenia Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 67
2010	Effects of simvastatin and 6-hydroxydopamine lesion on histaminergic H1 receptor binding in rat brains Published In ANS/AuPS 2010 - the 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society Pages 118 - 118
2010	Olanzapine decreases [3H]SR141716A binding to cannabinoid CB1 receptors in the rat hippocampus and auditory cortex: a dosage-dependent response Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 82
2010	Olanzapine-induced metabolic dysfunction: a role for central muscarinic M3 receptors Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 33
2010	The dosage response to the side-effect of metabolic dysfunction in female rats following olanzapine treatment Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 82
2009	Developmental vitamin D (DVD) deficiency alters MK-801 induced locomotion and glutamatergic rceptor binding Published In Australian Neuroscience Society Inc 29th Annual Meeting Pages 70 - 70
2009	Related pathological changes of serotonin 2A, muscarinic M1 and GABA A receptors in the superior temporal gyrus in schizophrenia Published In Australian Neuroscience Society Annual Meeting Page p. 37
2008	Cholecystokinin mRNA expression in the arcuate hypothalamic nuclei in diet-induced obese and obese resistant mice Published In 6th Forum of European Neuroscience Abstract Volume 4 Pages 094.2 - 094.2
2008	Neonatal interruption of NMDA receptors causes abnormal brain development and behavioural changes in adult rats Published In 35th Annual Australasian Society for the Study of Animal Behaviour Conference, Symposium on Brain and Behaviour Pages 8 - 9
2007	A negative association between the CB1 receptor mRNA expression and high fat intake during the course of diet-induced obesity in mice Published In 17th Neuropharmacology Conference: Cannabinoid Signalling in the Nervous System
2007	Antipsychotic drugs increase food intake and cannabinoid CB1 receptor mRNA expression in the brain of rats Published In 17th Neuropharmacology Conference: Cannabinoid Signalling in the Nervous System
2007	Effects of antipsychotic drugs on weight gain and CB1 receptors in the dorsal vagal complex of rats Published In 7th IBRO World Congress of Neuroscience Page p. 144
2007	Effects of antipsychotics on muscarinic M1 receptor mRNA expression in the rat brain Published In 7th IBRO World Congress of Neuroscience Page p. 275
2007	Effects of perinatal NMDA receptor antagonist treatment on dopaminergic system development and behaviour Published In 7th IBRO World Congress of Neuroscience Page p. 234
2007	Long-term consequences of early brain development disruption on neurochemical balance and behaviour Published In 7th IBRO World Congress of Neuroscience Page p. 367
2007	Phencyclidine induces apoptosis in the brain of neonatal but not adolescent and adult rats Published In 7th IBRO World Congress of Neuroscience Page p. 364
2007	The role of Pyy and H1 histamine receptor expression in chronic diet-induced obese and diet-resistant mice Published In 7th IBRO World Congress of Neuroscience Page p. 283

Editor Of

Book
- Mapping the Pathophysiology of Schizophrenia: Interactions Between Multiple Cellular Pathways. Switzerland. 2014

Investigator On

Year	Title
2019	GoBlot machines and Leica Objective Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2019	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2016 - 2019	Understanding the mechanisms for ameliorating/preventing antipsychotic-induced obesity in early life Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2017	Lumenera Infinity 2-5 microscope colour camera Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2016	Small animal stereotaxic instrument and microinjection unit Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2012 - 2016	Schizophrenia: reversal of antipsychotic drug-induced obesity and its related metabolic disorders Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013	Roles of muscarinic M3 receptors in antipsychotic-induced metabolic side-effects: prevention and treatment of anti-psychotic insulin dysregulation Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2012	SU 105 Stirling Underbench Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2011	Understanding the mechanisms of functionally selective drugs: implication for new generation antipsychotic drugs Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2010	Precellys 24 tissue homogenizer and digital microplate shaker Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2010	Schizophrenia: prevention and treatment of atypical antipsychotic drug-induced obesity Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	The Development vitam D model (DVD) as an animal model for schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant

Available as Research Supervisor

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Master of Philosophy	Effects of Antipsychotic Drug Treatment on the Brain Development of Young Rats	Leite, Joshua
Doctor of Philosophy	Biological and Psychological Correlates of major Depressive Disorder	Mills, Jessica
Master of Philosophy	Antipsychotic-induced Metabolic Side-Effects in Juvenile Poly (I:C) Rats	Hodgson, James
Doctor of Philosophy	An Ontology to represent dementia and dementia care knowledge in computer readable format	Zhang, Zhenyu
Doctor of Philosophy	A Systematic Study of Currently Used CDSS (Clinical Decision Support System) for Future Development of CDSS	Zheng-Long, Tsai

Research Areas

Selected Publications

Journal Article

Year	Title
2019	Early antipsychotic exposure affects NMDA and GABAA receptor binding in the brains of juvenile rats Published In Psychiatry Research Volume 273 Pages 739 - 745 ISSN 0165-1781 Altmetric
2019	Modulation by chronic antipsychotic administration of PKA- and GSK3β-mediated pathways and the NMDA receptor in rat ventral midbrain Published In Psychopharmacology Volume Online First Pages 1 - 11 ISSN 0033-3158 Altmetric
2019	Simvastatin improves olanzapine-induced dyslipidemia in rats through inhibiting hepatic mTOR signaling pathway Published In Acta Pharmacologica Sinica Volume Online First Pages 1 - 9 ISSN 1671-4083 Altmetric
2019	Weight gain in Major Depressive Disorder: Linking appetite and disordered eating to leptin and ghrelin. Published In Psychiatry Research Volume Online First Pages 1 - 8 ISSN 0165-1781 Altmetric
2018	BDNF as a pharmacogenetic target for antipsychotic treatment of schizophrenia Published In Neuroscience Letters Volume Online First Pages 1 - 5 ISSN 0304-3940 Altmetric
2018	Chronic antipsychotic treatment differentially modulates protein kinase A- and glycogen synthase kinase 3 beta-dependent signaling pathways, N-methyl-D-aspartate receptor and γ-aminobutyric acid A receptors in nucleus accumbens of juvenile rats Published In Journal of Psychopharmacology Volume 32 Pages 1252 - 1263 ISSN 0269-8811 Altmetric
2018	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the adult serotonin receptors Published In Neuropsychiatric Disease and Treatment Volume 14 Pages 1569 - 1583 ISSN 1176-6328 Altmetric
2018	Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol Published In Psychiatry Research Volume 260 Pages 152 - 157 ISSN 0165-1781 Altmetric
2018	Problematic eating behaviours, changes in appetite, and weight gain in Major Depressive Disorder: The role of leptin Published In Journal of Affective Disorders Volume 240 Pages 137 - 145 ISSN 1573-2517 Altmetric
2018	The effects of antipsychotics on the density of cannabinoid receptors in selected brain regions of male and female adolescent juvenile rats Published In Psychiatry Research Volume 266 Pages 317 - 322 ISSN 0165-1781 Altmetric
2017	Molecular mechanisms of antipsychotic drug-induced diabetes Published In Frontiers in Neuroscience Volume 11 Pages 643-1 - 643-12 ISSN 1662-453X Altmetric
2017	Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats Published In Scientific Reports Volume 7 Pages 2762-1 - 2762-13 ISSN 2045-2322 Altmetric
2017	Time-dependent effects of olanzapine treatment on the expression of histidine decarboxylase, H1 and H3 receptor in the rat brain: The roles in olanzapine-induced obesity Published In Psychoneuroendocrinology Volume 85 Pages 190 - 199 ISSN 0306-4530 Altmetric
2016	Ameliorating antipsychotic-induced weight gain by betahistine: mechanisms and clinical implications Published In Pharmacological Research Volume 106 Pages 51 - 63 ISSN 1096-1186 Altmetric
2016	Aripiprazole and haloperidol activate GSK3β-dependent signalling pathway differentially in various brain regions of rats Published In International Journal of Molecular Sciences Volume 17 Pages 459-1 - 459-11 ISSN 1661-6596 Altmetric
2016	Aripiprazole increases the PKA signalling and expression of the GABA_A receptor and CREB1 in the nucleus accumbens of rats Published In Journal of Molecular Neuroscience Volume 59 Pages 36 - 47 ISSN 0895-8696 Altmetric
2016	Berberine alleviates olanzapine-induced adipogenesis via the AMPKα-SREBP pathway in 3T3-L1 cells Published In International Journal of Molecular Sciences Volume 17 Pages 1865-1 - 1865-12 ISSN 1661-6596 Altmetric
2016	Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA_A receptor expression and CREB1 activity in rats Published In Scientific Reports Volume 6 Pages 30040-1 - 30040-12 ISSN 2045-2322 Altmetric
2016	Early antipsychotic exposure affects serotonin and dopamine receptor binding density differently in selected brain loci of male and female juvenile rats Published In Pharmacological Reports Volume 68 Pages 1028 - 1035 ISSN 1734-1140 Altmetric
2016	Early antipsychotic treatment in childhood/adolescent period has long-term effects on depressive-like, anxiety-like and locomotor behaviours in adult rats Published In Journal of Psychopharmacology Volume 30 Pages 204 - 214 ISSN 0269-8811 Altmetric
2016	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the dopamine neurotransmitter system Published In International Journal of Molecular Sciences Volume 17 Pages 1944-1 - 1944-20 ISSN 1661-6596 Altmetric
2016	Interaction of dopamine D₂ and 5-HT_1A receptor partial agonism on antipsychotic efficacy Published In Journal of Clinical Psychopharmacology Volume 36 Pages 192 - 193 ISSN 0271-0749 Altmetric
2016	Modelling complex relationships between physiological and psychosocial factors in depression Published In International Journal of Psychophysiology Volume 108 Page p. 357 ISSN 0167-8760 Altmetric
2016	Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6-hydroxydopamine lesioned rat brains Published In Life Sciences Volume 155 Pages 123 - 132 ISSN 0024-3205 Altmetric
2016	The second-generation antipsychotic drugs induced dyslipidemia: a review of research and mechanisms Published In Zhongguo Yaoxue Zazhi Volume 51 Pages 172 - 176 Altmetric
2015	Acute effects of oral olanzapine treatment on the expression of fatty acid and cholesterol metabolism-related gene in rats Published In Life Sciences Volume 128 Pages 72 - 78 ISSN 0024-3205 Altmetric
2015	Betahistine co-treatment ameliorates dyslipidemia induced by chronic olanzapine treatment in rats through modulation of hepatic AMPKα-SREBP-1 and PPARα-dependent pathways Published In Pharmacological Research Volume 100 Pages 36 - 46 ISSN 1096-1186 Altmetric
2015	Chronic betahistine co-treatment reverses olanzapine's effects on dopamine D2 but not 5-HT2A/2C bindings in rat brains Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 56 Pages 75 - 80 ISSN 0278-5846 Altmetric
2015	Differential effects of short- and long-term antipsychotic treatment on the expression of neuregulin-1 and ErbB4 receptors in the rat brain Published In Psychiatry Research Volume 225 Pages 347 - 354 ISSN 0165-1781 Altmetric
2015	Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases Published In Endocrine Volume 49 Pages 307 - 323 ISSN 1355-008X Altmetric
2015	Risperidone-induced weight gain and reduced locomotor activity in juvenile female rats: the role of histaminergic and NPY pathways Published In Pharmacological Research Volume 95-96 Pages 20 - 26 ISSN 1096-1186 Altmetric
2015	Unique effects of acute aripiprazole treatment on the dopamine D2 receptor downstream cAMP-PKA and Akt-GSK3β signalling pathways in rats Published In PLoS One Volume 10 Pages e0132722-1 - e0132722-20 ISSN 1932-6203 Altmetric
2014	Alterations of NMDA receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats Published In International Journal of Neuroscience Volume 124 Pages 457 - 465 ISSN 0020-7454 Altmetric
2014	Betahistine ameliorates olanzapine-induced weight gain through modulation of histaminergic, NPY and AMPK pathways Published In Psychoneuroendocrinology Volume 48 Pages 77 - 86 ISSN 0306-4530 Altmetric
2014	Different effects of Bifeprunox, Aripiprazole, and Haloperidol on body weight gain, food and water intake, and locomotor activity in rats Published In Pharmacology, Biochemistry and Behavior Volume 124 Pages 167 - 173 ISSN 1873-5177 Altmetric
2014	Effects of olanzapine on the elevation of macrophage infiltration and pro-inflammatory cytokine expression in female rats Published In Journal of Psychopharmacology Volume 28 Pages 1161 - 1169 ISSN 0269-8811 Altmetric
2014	Hypothalamic ghrelin signalling mediates olanzapine-induced hyperphagia and weight gain in female rats Published In International Journal of Neuropsychopharmacology Volume 17 Pages 807 - 818 ISSN 1461-1457 Altmetric
2014	Hypothalamic histamine H1 receptor-AMPK signaling time-dependently mediates olanzapine-induced hyperphagia and weight gain in female rats Published In Psychoneuroendocrinology Volume 42 Pages 153 - 164 ISSN 0306-4530 Altmetric
2014	Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics Published In Journal of Psychiatry and Neuroscience Volume 39 Pages 407 - 416 ISSN 0702-8466 Altmetric
2014	Olanzapine reduced brown adipose tissue thermogenesis and locomotor activity in female rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 51 Pages 172 - 180 ISSN 0278-5846 Altmetric
2014	Olanzapine-activated AMPK signaling in the dorsal vagal complex is attenuated by histamine H1 receptor agonist in female rats Published In Endocrinology Volume 155 Pages 4895 - 4904 ISSN 0013-7227 Altmetric
2014	Preventing olanzapine-induced weight gain using betahistine: a study in a rat model with chronic olanzapine treatment Published In PLoS One Volume 9 Pages e104160-1 - e104160-11 ISSN 1932-6203 Altmetric
2014	Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: the association with improvements in long-term memory Published In Neuroscience Volume 267 Pages 57 - 66 ISSN 0306-4522 Altmetric
2013	Effects of antipsychotic medications on appetite, weight, and insulin resistance Published In Endocrinology and Metabolism Clinics of North America Volume 42 Pages 545 - 563 ISSN 0889-8529 Altmetric
2013	Effects of olanzapine and betahistine co-treatment on serotonin transporter, 5-HT2A and dopamine D2 receptor binding density Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 47 Pages 62 - 68 ISSN 0278-5846 Altmetric
2013	Mapping the pathophysiology of schizophrenia: interactions between multiple cellular pathways Published In Frontiers in Cellular Neuroscience Volume 7 Pages 238-1 - 238-2 ISSN 1662-5102 Altmetric
2013	Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment Published In Schizophrenia Research Volume 146 Pages 170 - 176 ISSN 0920-9964 Altmetric
2013	Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway Published In Psychopharmacology Volume 226 Pages 201 - 215 ISSN 0033-3158 Altmetric
2013	Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor Published In CNS Drugs Volume 27 Pages 1069 - 1080 ISSN 1172-7047 Altmetric
2013	The association of antidepressant medication and body weight gain Published In Online Journal of Health and Allied Sciences Volume 12 Pages 1 - 9
2013	The role of ghrelin signalling in second-generation antipsychotic-induced weight gain Published In Psychoneuroendocrinology Volume 38 Pages 2423 - 2438 ISSN 0306-4530 Altmetric
2013	The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain Published In CNS Drugs Volume 27 Pages 423 - 434 ISSN 1172-7047 Altmetric
2012	Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain Published In PLoS One Volume 7 Pages e33548 - 1 - e33548 - 12 ISSN 1932-6203 Altmetric
2012	Are there different neural mechanisms responsible for three stages of weight gain development in anti-psychotic therapy: Temporally based hypothesis Published In Asian Journal of Psychiatry Volume 5 Pages 315 - 318 ISSN 1876-2018 Altmetric
2012	Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring Published In Psychopharmacology Volume 220 Pages 455 - 463 ISSN 0033-3158 Altmetric
2012	Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels Published In European Neuropsychopharmacology Volume 22 Pages 364 - 373 ISSN 0924-977X Altmetric
2012	Reducing olanzapine-induced weight gain side-effect by using betahistine: a study in the rat model Published In Journal of Psychopharmacology Volume 26 Pages 1271 - 1279 ISSN 0269-8811 Altmetric
2011	Antipsychotic treatment and neuregulin 1 -ErbB4 signalling in schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 35 Pages 924 - 930 ISSN 0278-5846 Altmetric
2011	Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats Published In Behavioural Brain Research Volume 217 Pages 337 - 346 ISSN 0166-4328 Altmetric
2011	Potential control of risperidone-related cognitive deficits by adjunctive aripiprazole treatment Published In Journal of Clinical Psychopharmacology Volume 31 Pages 135 - 136 ISSN 0271-0749 Altmetric
2011	Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses Published In PLoS One Volume 6 Pages e20945 - e20945 ISSN 1932-6203 Altmetric
2011	Statins: multiple neuroprotective mechanisms in neurodegenerative diseases Published In Experimental Neurology Volume 230 Pages 27 - 34 ISSN 0014-4886 Altmetric
2010	Alterations in 5-HT2A receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats Published In Synapse (New York) Volume 64 Pages 224 - 230 ISSN 0887-4476 Altmetric
2010	Effects of antipsychotic drugs on muscarinic M1 receptors in the rat brain Published In Australian and New Zealand Journal of Psychiatry Volume 44 Page p. A51 ISSN 1440-1614
2010	Effects of simvastatin and 6-hydroxydopamine on histaminergic H1 receptor binding density in rat brains Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 34 Pages 1419 - 1425 ISSN 0278-5846 Altmetric
2010	Effects of typical and atypical antipsychotics on the expressions of neuregulin 1 and ERBB4 receptors Published In Australian and New Zealand Journal of Psychiatry Volume 44 Pages A49 - A50 ISSN 1440-1614
2010	Molecular cloning and characterization of the global regulator LaeA in Penicillium citrinum Published In Biotechnology Letters Volume 32 Pages 1733 - 1737 ISSN 0141-5492 Altmetric
2010	Olanzapine decreases POMC MRNA expression and M3 receptors binding density in the hypothalamus and brainstem: pathway for weight gain side-effect? Published In Australian and New Zealand Journal of Psychiatry Volume 44 Page p. A55 ISSN 1440-1614
2010	Olanzapine decreases cannabinoid CB1 receptors in the hypothalamus and brainstem, possibly through muscarinic M3 receptor antagonism Published In International Journal of Neuropsychopharmacology Volume 13 Pages 111 - 112 ISSN 1461-1457 Altmetric
2010	Potential control of antipsychotic-induced hyperprolactinemia and obesity in children and adolescents by aripiprazole Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 34 Pages 1157 - 1158 ISSN 0278-5846 Altmetric
2010	Reduce the olanzapine-induced body weight gain with histamine H1 receptor agonist betahistine in rats Published In International Journal of Neuropsychopharmacology Volume 13 Page p. 99 ISSN 1461-1457 Altmetric
2010	Sensitivity of the female rat to olanzapine-induced weight gain - far from the clinic? Published In Schizophrenia Research Volume 116 Pages 299 - 300 ISSN 0920-9964 Altmetric
2010	The role of histaminergic H1 and H3 receptors in food intake:-A mechanism fo atypical antipsychotic-induced weight gain? Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 34 Pages 1 - 4 ISSN 0278-5846 Altmetric
2010	What is the mechanism for aripiprazole's effect on reducing olanzapine-associated obesity? Published In Journal of Clinical Psychopharmacology Volume 30 Pages 480 - 481 ISSN 0271-0749 Altmetric
2009	Aripiprazole differentially affects mesolimbic and nigrostriatal dopaminergic transmission: implications for long-term drug efficacy and low extrapyramidal side-effects Published In International Journal of Neuropsychopharmacology Volume 12 Pages 941 - 952 ISSN 1461-1457 Altmetric
2009	Decreased density of serotonin 2A receptors in the superior temporal gyrus in schizophrenia - a postmortem study Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 33 Pages 867 - 871 ISSN 0278-5846 Altmetric
2009	Excitatory and inhibitory neurotransmission is chronically altered following perinatal NMDA receptor blockade Published In European Neuropsychopharmacology Volume 19 Pages 256 - 265 ISSN 0924-977X Altmetric
2009	High dose of simvastatin induces hyperlocomotive and anxiolytic-like activities: the association with the up-regulation of NMDA receptor binding in the rat brain Published In Experimental Neurology Volume 216 Pages 132 - 138 ISSN 0014-4886 Altmetric
2009	Obese reversal by a chronic energy restricted diet leaves an increased Arc NPY/AgRP, but no alteration in POMC/CART, mRNA expression in diet-induced obese mice Published In Behavioural Brain Research Volume 205 Pages 50 - 56 ISSN 0166-4328 Altmetric
2009	Perinatal PCP treatment alters the developmental expression of prefrontal and hippocampal muscarinic receptors Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 33 Pages 37 - 40 ISSN 0278-5846 Altmetric
2009	Serotonin 2A receptor and its association with the pathology of schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 33 Pages 1585 - 1586 ISSN 0278-5846 Altmetric
2009	The effects of antipsychotic drugs administration on 5-HT1A receptor expression in the limbic system of the rat brain Published In Neuroscience Volume 164 Pages 1754 - 1763 ISSN 0306-4522 Altmetric
2008	Altered dopamine receptor and dopamine transporter binding and tyrosine hydroxylase mRNA expression following perinatal NMDA receptor blockade Published In Neurochemical Research Volume 33 Pages 1224 - 1231 ISSN 0364-3190 Altmetric
2008	Effects of antipsychotic medication on muscarinic M1 receptor mRNA expression in the rat brain Published In Journal of Neuroscience Research Volume 86 Pages 457 - 464 ISSN 0360-4012 Altmetric
2008	Perinatal NMDA receptor blockade alters D2, NMDA and M1/M4 receptors in later life: implications for pathological processes of schizophrenia Published In Schizophrenia Research Volume 102 Page p. 68 ISSN 0920-9964
2008	Perinatal administration of PCP alters adult behaviour in female Sprague-Dawley rats Published In Behavioural Brain Research Volume 188 Pages 416 - 419 ISSN 0166-4328 Altmetric
2008	Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression Published In Psychoneuroendocrinology Volume 33 Pages 569 - 580 ISSN 0306-4530 Altmetric
2008	The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: Implications for olanzapine-induced weight gain Published In International Journal of Neuropsychopharmacology Volume 11 Pages 827 - 835 ISSN 1461-1457 Altmetric
2008	Ventromedial hypothalamic NPY Y2 receptor in the maintenance of body weight in diet-induced obesity in mice Published In Neurochemical Research Volume 33 Pages 1881 - 1888 ISSN 0364-3190 Altmetric
2007	A rodent model of NMDA receptor hypofunction for the study of schizophrenia Published In Neuroscience Bulletin Volume 23 Pages 81 - 81 ISSN 1673-7067
2007	A static handgrip method for distal quantitative sweat measurements Published In Neuroscience Letters Volume 421 Pages 229 - 233 ISSN 0304-3940 Altmetric
2007	AM 251 and beta-Funaltrexamine reduce fat intake in a fat-preferring strain of mouse Published In Behavioural Brain Research Volume 181 Pages 153 - 157 ISSN 0166-4328 Altmetric
2007	Decreased plasma peptide YY accompanied by elevated peptide YY and Y2 receptor binding densities in the medulla oblongata of diet-induced obese mice Published In Endocrinology Volume 148 Pages 4704 - 4710 ISSN 0013-7227 Altmetric
2007	Dose-dependent effects of atypical antipsychotic drug olanzapine on weight gain and cholecystokinin levels in rats Published In Neuroscience Bulletin Volume 23 Pages 352 - 352 ISSN 1673-7067
2007	Histamine H1 mRNA expression is decreased in the rat hypothalamus following olanzapine treatment Published In Schizophrenia Bulletin Volume 33 Page p. 317 ISSN 0586-7614
2007	NMDA receptor hypofunction during early brain development: relevance to schizophrenia Published In Schizophrenia Bulletin Volume 33 Page p. 317 ISSN 0586-7614
2007	No changes in cannabinoid CB1 receptor binding density in the superior temporal gyrus in schizophrenia Published In Schizophrenia Bulletin Volume 33 Pages 308 - 309 ISSN 0586-7614
2007	No changes in densities of cannabinoid receptors in the superior temporal gyrus in schizophrenia Published In Neuroscience Bulletin Volume 23 Pages 341 - 347 ISSN 1673-7067 Altmetric
2007	Olanzapine treatment decreases the density of muscarinic M2 receptors in the dorsal vagal complex of rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 31 Pages 915 - 920 ISSN 0278-5846 Altmetric

Conference Paper

Year	Title
2017	Relationships of hormone levels with hunger, weight gain and problematic eating behaviours in Major Depressive Disorder Published In Frontiers in Human Neuroscience Abstract: ASP2017 27th Annual Meeting for the Australasian Society for Psychophysiology Pages 1 - 1 Altmetric
2013	An analysis of metabotropic glutamate receptors 2/3 and 5 in schizophrenia, major depression and bipolar disorder from the stanley neuropathology consortium Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 49 - 49
2013	Binding affinity of aripiprazole to the dopamine D2 receptor in different regions of the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 115 - 115
2013	Central administration of histamine H1 receptor agonist, fMPH, blocks olanzapineinduced activation of ampk-cpt1 signaling in the dorsal vagal complex in rats Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 120 - 120
2013	Effects of chronic antipsychotic treatment on dopamine synthesis Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 115 - 115
2013	Long term effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 171 - 171
2013	Time-dependent ghrelinergic signaling and hyperphagia induced by olanzapine Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants Pages 48 - 48
2012	Differential effects of aripiprazole and haloperidol on dopamine markers in the arcuate nucleus and prolactin levels in male rats Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology Pages 60 - 60 Altmetric
2012	Effects of dopamine D2 receptor partial agonist bifeprunox on body weight gain, food and water intake in male rats Published In Australian Neuroscience Society 32nd Annual meeting Pages 150 - 150
2012	Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain Published In ANS 2012: Australian Neuroscience Society 32nd Annual meeting Page p. 97
2012	MGluR5 and NMDA receptor density are reduced in the dorsolateral prefrontal cortex of schizoaffective but not schizophrenia patients Published In Society of Biological Psychiatry 67th Annual Meeting
2012	Metabotropic glutamate receptor subtype 5 is reduced in schizophrenia subjects with comorbid major depression and unchanged following antipsychotic drug treatment Published In Australian Neuroscience Society 32nd Annual meeting Pages 95 - 95
2012	Olanzapine treatment and time-dependent changes of hypothalamic AMPK-ACC-CPT1 signalling, food intake and body weight in rats Published In ANS 2012: Australian Neuroscience Society 32nd Annual meeting Pages 148 - 148
2012	Preventing and treating olanzapine-induced obesity with betahistine: a chronic animal model study Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology Pages 56 - 56 Altmetric
2012	Time-dependant alterations of hypothalamic energy regulatory network by olanzapine in rats Published In Australian Neuroscience Society 32nd Annual meeting Pages 150 - 150
2011	Aripiprazole selectively affects AKT/GSK protein expression in the nucleus accumbens and caudate putamen Published In 31st Annual Meeting of the Australian Neuroscience Society Pages 54 - 54
2011	Histamine H1 receptor agonist and control of olanzapine-induced obesity Published In 31st Annual Meeting of the Australian Neuroscience Society Pages 126 - 126
2011	Neuroendocrinological regulation of insulin dysfunction induced by olanzapine Published In 31st Annual Meeting of the Australian Neuroscience Society Pages 54 - 54
2010	An age difference in mu opioid receptor binding density in the human putamen but no changes in schizophrenia Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 67
2010	Effects of simvastatin and 6-hydroxydopamine lesion on histaminergic H1 receptor binding in rat brains Published In ANS/AuPS 2010 - the 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society Pages 118 - 118
2010	Olanzapine decreases [3H]SR141716A binding to cannabinoid CB1 receptors in the rat hippocampus and auditory cortex: a dosage-dependent response Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 82
2010	Olanzapine-induced metabolic dysfunction: a role for central muscarinic M3 receptors Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 33
2010	The dosage response to the side-effect of metabolic dysfunction in female rats following olanzapine treatment Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 82
2009	Developmental vitamin D (DVD) deficiency alters MK-801 induced locomotion and glutamatergic rceptor binding Published In Australian Neuroscience Society Inc 29th Annual Meeting Pages 70 - 70
2009	Related pathological changes of serotonin 2A, muscarinic M1 and GABA A receptors in the superior temporal gyrus in schizophrenia Published In Australian Neuroscience Society Annual Meeting Page p. 37
2008	Cholecystokinin mRNA expression in the arcuate hypothalamic nuclei in diet-induced obese and obese resistant mice Published In 6th Forum of European Neuroscience Abstract Volume 4 Pages 094.2 - 094.2
2008	Neonatal interruption of NMDA receptors causes abnormal brain development and behavioural changes in adult rats Published In 35th Annual Australasian Society for the Study of Animal Behaviour Conference, Symposium on Brain and Behaviour Pages 8 - 9
2007	A negative association between the CB1 receptor mRNA expression and high fat intake during the course of diet-induced obesity in mice Published In 17th Neuropharmacology Conference: Cannabinoid Signalling in the Nervous System
2007	Antipsychotic drugs increase food intake and cannabinoid CB1 receptor mRNA expression in the brain of rats Published In 17th Neuropharmacology Conference: Cannabinoid Signalling in the Nervous System
2007	Effects of antipsychotic drugs on weight gain and CB1 receptors in the dorsal vagal complex of rats Published In 7th IBRO World Congress of Neuroscience Page p. 144
2007	Effects of antipsychotics on muscarinic M1 receptor mRNA expression in the rat brain Published In 7th IBRO World Congress of Neuroscience Page p. 275
2007	Effects of perinatal NMDA receptor antagonist treatment on dopaminergic system development and behaviour Published In 7th IBRO World Congress of Neuroscience Page p. 234
2007	Long-term consequences of early brain development disruption on neurochemical balance and behaviour Published In 7th IBRO World Congress of Neuroscience Page p. 367
2007	Phencyclidine induces apoptosis in the brain of neonatal but not adolescent and adult rats Published In 7th IBRO World Congress of Neuroscience Page p. 364
2007	The role of Pyy and H1 histamine receptor expression in chronic diet-induced obese and diet-resistant mice Published In 7th IBRO World Congress of Neuroscience Page p. 283

Editor Of

Book
- Mapping the Pathophysiology of Schizophrenia: Interactions Between Multiple Cellular Pathways. Switzerland. 2014

Investigator On

Year	Title
2019	GoBlot machines and Leica Objective Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2019	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2016 - 2019	Understanding the mechanisms for ameliorating/preventing antipsychotic-induced obesity in early life Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2017	Lumenera Infinity 2-5 microscope colour camera Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2016	Small animal stereotaxic instrument and microinjection unit Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2012 - 2016	Schizophrenia: reversal of antipsychotic drug-induced obesity and its related metabolic disorders Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013	Roles of muscarinic M3 receptors in antipsychotic-induced metabolic side-effects: prevention and treatment of anti-psychotic insulin dysregulation Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2012	SU 105 Stirling Underbench Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2011	Understanding the mechanisms of functionally selective drugs: implication for new generation antipsychotic drugs Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2010	Precellys 24 tissue homogenizer and digital microplate shaker Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2010	Schizophrenia: prevention and treatment of atypical antipsychotic drug-induced obesity Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	The Development vitam D model (DVD) as an animal model for schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Master of Philosophy	Effects of Antipsychotic Drug Treatment on the Brain Development of Young Rats	Leite, Joshua
Doctor of Philosophy	Biological and Psychological Correlates of major Depressive Disorder	Mills, Jessica
Master of Philosophy	Antipsychotic-induced Metabolic Side-Effects in Juvenile Poly (I:C) Rats	Hodgson, James
Doctor of Philosophy	An Ontology to represent dementia and dementia care knowledge in computer readable format	Zhang, Zhenyu
Doctor of Philosophy	A Systematic Study of Currently Used CDSS (Clinical Decision Support System) for Future Development of CDSS	Zheng-Long, Tsai

Deng, Chao Prof

Professor, Head of Antipsychotic Research Laboratory

Overview

Research Areas

Available as Research Supervisor

Publications

Selected Publications

Journal Article

Conference Paper

Editor Of

Book

Funding

Investigator On

Supervision

Available as Research Supervisor

Advisees

Graduate Advising Relationship

Overview

Research Areas

Publications

Selected Publications

Journal Article

Conference Paper

Editor Of

Book

Funding

Investigator On

Supervision

Advisees

Graduate Advising Relationship

Visualisations

Research Areas