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Kelso, Celine Dr

Mass Spectrometry Facility Manager

  • Faculty of Science, Medicine and Health
  • School of Chemistry

Overview


My research focuses on utilising mass spectrometry and allied techniques (GC, HPLC and UPLC) to answer a range of different research questions, including analysis of biomolecules (DNA, Proteins) and small molecules.

Top Publications


Available as Research Supervisor

Selected Publications


Available as Research Supervisor

Potential Supervision Topics


  • Honours Project 2019 : Are all e-cigarette fluids created equal?

    Co-supervisors: Dr Jody Moller and Dr Celine Kelso

    Electronic cigarettes, more commonly referred to as e-cigarettes or “vape pens”, work by heating a liquid, which often contains nicotine, to form a vapour that can be inhaled in a process colloquially referred to as ‘vaping’. Analysis of e-cigarette vapour has found that while toxicants are present, they are orders of magnitude lower than the levels found in combustible cigarettes making them a useful tool for those wishing to quit traditional cigarettes. In Australia, the sale or supply of nicotine-containing e-cigarette fluids is currently illegal due to nicotine’s high toxicity, however, consumers are able to import nicotine-containing e-cigarette fluid or obtain these products via an Australian-based compounding pharmacy, provided they have a pharmaceutical prescription. This process avoids analytical validation of products by the TGA and strict requirements for child-proof packaging of harmful materials. This project in collaboration with Prof. Alison Jones MD aims to analyse e-cigarette fluids currently available to Australian consumers from a variety of sources to determine: a) if liquids being sold within Australia contain nicotine, contravening current regulations; b) if imported samples and e-cigarette fluids sourced from compounding pharmacies contain accurate nicotine concentrations which are below toxicity recommendations; c) if direct fluid analysis and captured vapour analysis produce comparable results; and d) if the e-cigarette vapour examined contains toxic pyrolysis products such as formaldehyde and benzaldehyde. This project will develop your research skills in small molecule analysis using techniques such as GC-MS, HPLC and NMR and you can be involved in toxicological research that has the potential to change the direction of health policy in Australia.

Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Synthesis and Quadruplex DNA Binding Properties of Novel Nickel Schiff base complexes Pham, Quynh Thai Son
    Doctor of Philosophy An Investigation Into the Struture of Protein Toxins of Australian Snake Venoms Structure to Therapeutics Harrison, Julian
    Doctor of Philosophy Developing a sustainable method for analysing the anthocyanin content of commodities in the Australian and Indian food supply Chandra Singh, Mamatha

Education And Training


  • D.Phil. in Mass Spectrometry, School of Chemistry, Investigation of the DNA-Binding Porperties of Cosmomycin D, an Uncommon Anthracycline Compound 2006 - 2010
  • M.Sc. in Organic Chemistry and Biochemistry Structural Studies, University of Paris VI 2004

Full Name


  • Dr Celine Kelso

Mailing Address


  • University of Wollongong

    School of Chemistry, Bld 18, Room 104

    Wollongong

    NSW

    2522

    Australia

Web Of Science Researcher Id


  •  E-2679-2016

Top Publications


Selected Publications


Potential Supervision Topics


  • Honours Project 2019 : Are all e-cigarette fluids created equal?

    Co-supervisors: Dr Jody Moller and Dr Celine Kelso

    Electronic cigarettes, more commonly referred to as e-cigarettes or “vape pens”, work by heating a liquid, which often contains nicotine, to form a vapour that can be inhaled in a process colloquially referred to as ‘vaping’. Analysis of e-cigarette vapour has found that while toxicants are present, they are orders of magnitude lower than the levels found in combustible cigarettes making them a useful tool for those wishing to quit traditional cigarettes. In Australia, the sale or supply of nicotine-containing e-cigarette fluids is currently illegal due to nicotine’s high toxicity, however, consumers are able to import nicotine-containing e-cigarette fluid or obtain these products via an Australian-based compounding pharmacy, provided they have a pharmaceutical prescription. This process avoids analytical validation of products by the TGA and strict requirements for child-proof packaging of harmful materials. This project in collaboration with Prof. Alison Jones MD aims to analyse e-cigarette fluids currently available to Australian consumers from a variety of sources to determine: a) if liquids being sold within Australia contain nicotine, contravening current regulations; b) if imported samples and e-cigarette fluids sourced from compounding pharmacies contain accurate nicotine concentrations which are below toxicity recommendations; c) if direct fluid analysis and captured vapour analysis produce comparable results; and d) if the e-cigarette vapour examined contains toxic pyrolysis products such as formaldehyde and benzaldehyde. This project will develop your research skills in small molecule analysis using techniques such as GC-MS, HPLC and NMR and you can be involved in toxicological research that has the potential to change the direction of health policy in Australia.

Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Synthesis and Quadruplex DNA Binding Properties of Novel Nickel Schiff base complexes Pham, Quynh Thai Son
    Doctor of Philosophy An Investigation Into the Struture of Protein Toxins of Australian Snake Venoms Structure to Therapeutics Harrison, Julian
    Doctor of Philosophy Developing a sustainable method for analysing the anthocyanin content of commodities in the Australian and Indian food supply Chandra Singh, Mamatha

Education And Training


  • D.Phil. in Mass Spectrometry, School of Chemistry, Investigation of the DNA-Binding Porperties of Cosmomycin D, an Uncommon Anthracycline Compound 2006 - 2010
  • M.Sc. in Organic Chemistry and Biochemistry Structural Studies, University of Paris VI 2004

Full Name


  • Dr Celine Kelso

Mailing Address


  • University of Wollongong

    School of Chemistry, Bld 18, Room 104

    Wollongong

    NSW

    2522

    Australia

Web Of Science Researcher Id


  •  E-2679-2016