Larance, Briony Dr

Head Of

• Board of Management, Drug and Alcohol Multicultural Education Centre Chairperson 2018 -

Member Of

• APSAD Conference Scientific Programming Committee 2020 -
• ISLHD Drug and Alcohol Research Committee 2018 -
• SMART Recovery Australia Research Advisory Committee 2018 -

Selected Publications

• Journal Article

  Year	Title
  2022	Economic analysis of out-of-pocket costs among people in opioid agonist treatment: A cross-sectional survey in three Australian jurisdictions Published In International Journal of Drug Policy
  2022	Examining the cost and impact of dosing fees among clients in opioid agonist treatment: Results from a cross-sectional survey of Australian treatment clients Published In Drug and Alcohol Review
  2022	Outcomes of a single-arm implementation trial of extended-release subcutaneous buprenorphine depot injections in people with opioid dependence Published In International Journal of Drug Policy
  2022	Self-reported challenges obtaining ongoing prescription opioids among Australians with chronic non-cancer pain Published In International Journal of Drug Policy
  2021	Characteristics and circumstances of death related to buprenorphine toxicity in Australia Published In Drug and Alcohol Dependence
  2021	Clinical correlates and outcomes associated with pregabalin use among people prescribed opioids for chronic non-cancer pain: A five-year prospective cohort study Published In British Journal of Clinical Pharmacology
  2021	Eating Disorder Behaviours and Substance Use in Women Attending Treatment for Substance Use Disorders: a Latent Class Analysis Published In International Journal of Mental Health and Addiction
  2021	Facilitators and barriers to integrating physical health care during treatment for substance use: A socio-ecological analysis Published In Drug and Alcohol Review
  2021	Feasibility of a mobile health app for routine outcome monitoring and feedback in SMART recovery mutual support groups: Stage 1 mixed methods pilot study Published In Journal of Medical Internet Research
  2021	Perceptions of injectable opioid agonist treatment (iOAT) among people who regularly use opioids in Australia: findings from a cross-sectional study in three Australian cities Published In Addiction
  2021	Pharmaceutical Opioid Use Patterns and Indicators of Extramedical Use and Harm in Adults with Chronic Noncancer Pain, 2012-2018 Published In JAMA Network Open
  2021	Preliminary psychometric evaluation of the patient reported experience measure for addiction treatment (PREMAT) Published In Addictive Behaviors
  2021	Routine outcome measurement in specialist non-government alcohol and other drug treatment services: Establishing effectiveness indicators for the NADAbase Published In Drug and Alcohol Review
  2021	SMART Recovery International and COVID-19: Expanding the reach of mutual support through online groups Published In Journal of Substance Abuse Treatment
  2021	The use of Australian SMART Recovery groups by people who use methamphetamine: Analysis of routinely-collected nationwide data Published In Drug and Alcohol Dependence
  2020	A population-based study of transdermal fentanyl initiation in Australian clinical practice Published In European Journal of Clinical Pharmacology
  2020	A protocol for a discrete choice experiment: Understanding patient medicine preferences for managing chronic non-cancer pain Published In BMJ Open
  2020	Antidepressant Use Among People Prescribed Opioids for Chronic Noncancer Pain Published In Pain Medicine
  2020	Circumstances of death of opioid users being treated with naltrexone Published In Addiction
  2020	Concerns and Help-Seeking Among Patients Using Opioids for Management of Chronic Noncancer Pain Published In Pain Medicine
  2020	Effectiveness and framing of pharmaceutical opioid abuse-deterrent formulations Published In Addiction
  2020	Health care engagement behaviors of men who use performance- and image-enhancing drugs in Australia Published In Substance Abuse
  2020	Increases in controlled-release oxycodone utilisation following the subsidy of oxycodone with naloxone formulations: An Australian population-based study Published In Pharmacoepidemiology and Drug Safety
  2020	Post‐marketing studies of pharmaceutical opioid abuse‐deterrent formulations: a framework for research design and reporting Published In Addiction
  2020	Regulatory and other responses to the pharmaceutical opioid problem Published In Medical Journal of Australia
  2020	Regulatory and other responses to the pharmaceutical opioid problem Published In Medical Journal of Australia
  2020	Trends in methamphetamine and opioid use among clients of needle-syringe programs in Queensland, Australia: 2007–2015 Published In Drug and Alcohol Review
  2020	Correlates of indicators of potential extra-medical opioid use in people prescribed opioids for chronic non-cancer pain Published In Drug and Alcohol Review
  2020	Development of a brief patient-administered screening tool for prescription opioid dependence for primary care settings Published In Pain Medicine (United States)
  2020	Feasibility of a mobile health app for routine outcome monitoring and feedback in mutual support groups coordinated by SMART recovery Australia: Protocol for a pilot study Published In JMIR Research Protocols
  2020	Open-label, multicentre, single-arm trial of monthly injections of depot buprenorphine in people with opioid dependence: Protocol for the CoLAB study Published In BMJ Open
  2020	Opioid use and harms associated with a sustained-release tapentadol formulation: A post-marketing surveillance study Published In Drug and Alcohol Dependence
  2020	Perceptions of extended-release buprenorphine injections for opioid use disorder among people who regularly use opioids in Australia Published In Addiction
  2020	Risk factors for indicators of opioid-related harms amongst people living with chronic non-cancer pain: Findings from a 5-year prospective cohort study Published In EClinicalMedicine
  2020	Substance Use and Co-occurring Physical Health Problems: File Review of a Residential Drug and Alcohol Treatment Service Published In Journal of Dual Diagnosis
  2019	A population-based study of transdermal fentanyl initiation in Australian clinical practice Published In European Journal of Clinical Pharmacology
  2019	A protocol for a discrete choice experiment: Understanding patient medicine preferences for managing chronic non-cancer pain Published In BMJ Open
  2019	Antidepressant Use Among People Prescribed Opioids for Chronic Noncancer Pain Published In Pain Medicine
  2019	Circumstances of death of opioid users being treated with naltrexone Published In Addiction
  2019	Concerns and Help-Seeking Among Patients Using Opioids for Management of Chronic Noncancer Pain Published In Pain Medicine
  2019	Effectiveness and framing of pharmaceutical opioid abuse-deterrent formulations Published In Addiction
  2019	Health care engagement behaviors of men who use performance- and image-enhancing drugs in Australia Published In Substance Abuse
  2019	Increases in controlled-release oxycodone utilisation following the subsidy of oxycodone with naloxone formulations: An Australian population-based study Published In Pharmacoepidemiology and Drug Safety
  2019	Post‐marketing studies of pharmaceutical opioid abuse‐deterrent formulations: a framework for research design and reporting Published In Addiction
  2019	Regulatory and other responses to the pharmaceutical opioid problem Published In Medical Journal of Australia
  2019	Regulatory and other responses to the pharmaceutical opioid problem Published In Medical Journal of Australia
  2019	Trends in methamphetamine and opioid use among clients of needle-syringe programs in Queensland, Australia: 2007–2015 Published In Drug and Alcohol Review
  2018	A nationwide study of the extent and factors associated with fentanyl use in Australia Published In Research in Social and Administrative Pharmacy
  2018	Alcohol use disorder and associated physical health complications and treatment amongst individuals with and without opioid dependence: A case-control study Published In Drug and Alcohol Dependence
  2018	Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study Published In The Lancet Public Health
  2018	Knowledge of Opioid Overdose and Attitudes to Supply of Take-Home Naloxone Among People with Chronic Noncancer Pain Prescribed Opioids Published In Pain Medicine
  2018	Opioid use and harms associated with a sustained-release tapentadol formulation: a postmarketing study protocol Published In BMJ Open
  2018	Perceived stigma and social support in treatment for pharmaceutical opioid dependence Published In Drug and Alcohol Review
  2018	Person-level changes in oxycodone use after the introduction of a tamper-resistant formulation in Australia Published In CMAJ
  2018	Pharmaceutical opioid use and harm in Australia: The need for proactive and preventative responses Published In Drug and Alcohol Review
  2018	Physical appearance concerns are uniquely associated with the severity of steroid dependence and depression in anabolic–androgenic steroid users Published In Drug and Alcohol Review
  2018	Predictors of transitions across stages of heroin use and dependence prior to treatment-seeking among people in treatment for opioid dependence Published In Drug and Alcohol Dependence
  2018	Prescription Opioid Access Patterns and Factors Associated with Increasing Number of Prescribers, Pharmacies, and Dispensings: An Observational Study Using Pharmaceutical Claims Published In Pain Medicine
  2018	The effect of a potentially tamper-resistant oxycodone formulation on opioid use and harm: main findings of the National Opioid Medications Abuse Deterrence (NOMAD) study Published In The Lancet Psychiatry
  2018	To what extent do data from pharmaceutical claims under‐estimate opioid analgesic utilisation in Australia? Published In Pharmacoepidemiology and Drug Safety
  2018	Understanding an emerging treatment population: Protocol for and baseline characteristics of a prospective cohort of people receiving treatment for pharmaceutical opioid dependence Published In Drug and Alcohol Review
  2017	A systematic review of opioid agonist treatments for pharmaceutical opioid dependence Published In Drug and Alcohol Dependence
  2017	Defined daily doses (DDD) do not accurately reflect opioid doses used in contemporary chronic pain treatment Published In Pharmacoepidemiology and Drug Safety
  2017	Defining problematic pharmaceutical opioid use among people prescribed opioids for chronic non-cancer pain: Different measures, same patients? Published In Drug and Alcohol Dependence
  2017	Opioid Agonist Treatment for Patients With Dependence on Prescription Opioids Published In JAMA: Journal of the American Medical Association
  2017	Protecting Pain Patients. The Evaluation of a Chronic Pain Educational Intervention Published In Pain Medicine
  2017	Same-day use of opioids and depressants: A retrospective diary study Published In Drug and Alcohol Dependence
  2017	Trends in PIEDs use among male clients of needle–syringe programs in Queensland, Australia; 2007–2015 Published In International Journal of Drug Policy
  2016	A Typology of Predictive Risk Factors for Non-Adherent Medication-Related Behaviors among Chronic Non-Cancer Pain Patients Prescribed Opioids: A Cohort Study Published In Pain Physician
  2016	A cross‐sectional study of correlates of imprisonment in opioid‐dependent men and women in New South Wales, Australia Published In Drug and Alcohol Review
  2016	Alprazolam use and related harm among opioid substitution treatment clients – 12 months follow up after regulatory rescheduling Published In International Journal of Drug Policy
  2016	An ecological study of the extent and factors associated with the use of prescription and over-the-counter codeine in Australia Published In European Journal of Clinical Pharmacology
  2016	Defining problematic pharmaceutical opioid use among people prescribed opioids for chronic noncancer pain: do different measures identify the same patients? Published In Pain
  2016	Development of a brief tool for monitoring aberrant behaviours among patients receiving long-term opioid therapy: The Opioid-Related Behaviours In Treatment (ORBIT) scale Published In Drug and Alcohol Dependence
  2016	Diversion and injection of buprenorphine–naloxone film two years post‐introduction in Australia Published In Drug and Alcohol Review
  2016	Geographic Variation in Health Service Use and Perceived Access Barriers for Australian Adults with Chronic Non-Cancer Pain Receiving Opioid Therapy Published In Pain Medicine
  2016	Initiation of strong prescription opioids in Australia: cohort characteristics and factors associated with the type of opioid initiated Published In British Journal of Clinical Pharmacology
  2016	Opioid agonist treatment for pharmaceutical opioid dependent people (Review) Published In Cochrane Database of Systematic Reviews
  2016	Pain, alcohol use disorders and risky patterns of drinking among people with chronic non-cancer pain receiving long-term opioid therapy Published In Drug and Alcohol Dependence
  2016	Same-day use of opioids and other central nervous system depressants amongst people who tamper with pharmaceutical opioids: A retrospective 7-day diary study Published In Drug and Alcohol Dependence
  2016	Sleep Quality Among People Living With Chronic Noncancer Pain: Findings From the Pain and Opioids IN Treatment (POINT) Cohort Published In Clinical Journal of Pain
  2016	The extent and correlates of community‐based pharmaceutical opioid utilisation in Australia Published In Pharmacoepidemiology and Drug Safety
  2016	The extramedical use and diversion of opioid substitution medications and other medications in prison settings in Australia following the introduction of buprenorphine–naloxone film Published In Drug and Alcohol Review
  2015	A longitudinal comparison of retention in buprenorphine and methadone treatment for opioid dependence in New South Wales, Australia Published In Addiction
  2015	A typology of people who tamper with pharmaceutical opioids: responses to introduction of a tamper‐resistant formulation of controlled‐release oxycodone Published In Pharmacoepidemiology and Drug Safety
  2015	Agreement between definitions of pharmaceutical opioid use disorders and dependence in people taking opioids for chronic non-cancer pain (POINT): a cohort study Published In The Lancet Psychiatry
  2015	Benzodiazepine Use among Chronic Pain Patients Prescribed Opioids: Associations with Pain, Physical and Mental Health, and Health Service Utilization Published In Pain Medicine
  2015	Benzodiazepine use among a sample of chronic pain patients prescribed opioids Published In Drug and Alcohol Dependence
  2015	Evaluating the potential impact of a reformulated version of oxycodone upon tampering, non‐adherence and diversion of opioids: the National Opioid Medications Abuse Deterrence (NOMAD) study protocol Published In Addiction
  2015	Factors associated with the development of depression in chronic non-cancer pain patients following the onset of opioid treatment for pain Published In Journal of Affective Disorders
  2015	Injecting buprenorphine‐naloxone film: Findings from an explorative qualitative study Published In Drug and Alcohol Review
  2015	Jurisdictional differences in opioid use, other licit and illicit drug use, and harms associated with substance use among people who tamper with pharmaceutical opioids Published In Drug and Alcohol Review
  2015	Methods and predictors of tampering with a tamper-resistant controlled-release oxycodone formulation Published In International Journal of Drug Policy
  2015	Opioid therapy for chronic non-cancer pain: Does typology of risk predict aberrant behaviour? Published In Drug and Alcohol Dependence
  2015	Pharmaceutical Opioid Use and Dependence among People Living with Chronic Pain: Associations Observed within the Pain and Opioids in Treatment (POINT) Cohort Published In Pain Medicine
  2015	Pharmaceutical opioid use and dependence among people living with chronic pain: Associations observed within the pain and opioids in treatment cohort Published In Drug and Alcohol Dependence
  2015	Reducing extramedical use and harms of pharmaceutical opioids: the potential role of abuse-deterrent formulations Published In The Lancet Psychiatry
  2015	Sex differences in alcohol use disorders and risky drinking among chronic non-cancer pain patients receiving opioid therapy Published In Drug and Alcohol Dependence
  2015	The POPPY Research Programme protocol: investigating opioid utilisation, costs and patterns of extramedical use in Australia Published In BMJ Open
  2015	The Pain and Opioids IN Treatment study: characteristics of a cohort using opioids to manage chronic non-cancer pain Published In Pain
  2015	The characteristics of a cohort who tamper with prescribed and diverted opioid medications Published In Journal of Substance Abuse Treatment
  2015	The introduction of a potentially abuse deterrent oxycodone formulation: Early findings from the Australian National Opioid Medications Abuse Deterrence (NOMAD) study Published In Drug and Alcohol Dependence
  2015	The introduction of buprenorphine‐naloxone film in opioid substitution therapy in Australia: Uptake and issues arising from changing buprenorphine formulations Published In Drug and Alcohol Review
  2015	The use of paracetamol (acetaminophen) among a community sample of people with chronic non‐cancer pain prescribed opioids Published In International Journal of Clinical Practice
  2015	Xamining DSM and ICD definitions of pharmaceutical opioid dependence in people taking opioids for chronic pain: Findings from the pain and opioids in treatment study Published In Drug and Alcohol Dependence
  2014	A comparative study of opioid substitution therapy utilisation among opioid‐dependent men and women Published In Drug and Alcohol Review
  2014	A latent class analysis of self-reported clinical indicators of psychosocial stability and adherence among opioid substitution therapy patients: Do stable patients receive more unsupervised doses? Published In Drug and Alcohol Dependence
  2014	Australian post-marketing surveillance studies, 2012 Published In Drug and Alcohol Dependence
  2014	Cohort protocol paper: The Pain and Opioids In Treatment (POINT) study Published In BMC Pharmacology and Toxicology
  2014	Diversion of prescribed opioids by people living with chronic pain: Results from an Australian community sample Published In Drug and Alcohol Review
  2014	Is pain associated with illicit opioid use or aberrant opioid-related behaviors in opioid substitution treatment patients Published In Drug and Alcohol Dependence
  2014	Opioid agonist treatment for pharmaceutical opioid dependent people (Protocol) Published In Cochrane Database of Systematic Reviews
  2014	The diversion and injection of a buprenorphine-naloxone soluble film formulation Published In Drug and Alcohol Dependence
  2013	A randomised controlled trial of sublingual buprenorphine–naloxone film versus tablets in the management of opioid dependence Published In Drug and Alcohol Dependence
  2013	Correlates of pain in an in‐treatment sample of opioid‐dependent people Published In Drug and Alcohol Review
  2013	Estimating the proportion of prescription opioids that is consumed by people who inject drugs in Australia Published In Drug and Alcohol Review
  2011	Definitions related to the use of pharmaceutical opioids: Extramedical use, diversion, non-adherence and aberrant medication-related behaviours Published In Drug and Alcohol Review
  2011	Post-marketing surveillance of buprenorphine-naloxone in Australia: Diversion, injection and adherence with supervised dosing Published In Drug and Alcohol Dependence
  2011	Prescribers' perceptions of the diversion and injection of medication by opioid substitution treatment patients Published In Drug and Alcohol Review
  2011	Prescription of opioid analgesics and related harms in Australia Published In Medical Journal of Australia
  2011	The availability, diversion and injection of pharmaceutical opioids in South Asia Published In Drug and Alcohol Review
  2011	The prevalence and correlates of buprenorphine inhalation amongst opioid substitution treatment (OST) clients in Australia Published In International Journal of Drug Policy
  2009	Injection of medications used in opioid substitution treatment in Australia after the introduction of a mixed partial agonist-antagonist formulation Published In Medical Journal of Australia
  2008	Drug dependence and associated risks among female street-based sex workers in the greater Sydney area, Australia Published In Substance Use and Misuse
  2008	Injecting risk behaviour and related harm among men who use performance- and image-enhancing drugs Published In Drug and Alcohol Review

• Chapter

  Year	Title
  2020	Opioids Published In New Oxford Textbook of Psychiatry Publisher Oxford University Press

• Conference Paper

  Year	Title
  2020	Drawing on regional data analytics and stakeholder consultation to improve responses to methamphetamine-related harm in a New South Wales Local Health District Published In National Centre for Clinical Research on Emerging Drugs Inaugural Symposium
  2019	Drawing on regional data analytics and stakeholder consultation to improve responses to methamphetamine-related harm in a New South Wales Local Health District Published In National Centre for Clinical Research on Emerging Drugs Inaugural Symposium

• Other Publications

  Year	Title
  2015	Understanding the health and service needs of diverse populations of pharmaceutical opioid users: Cohort studies of dependent users in treatment, and people who inject drugs

Investigator On

Year	Title
2021 - 2022	Building peer and provider capacity to effectively deliver SMART Family and friends meetings: A two stage mixed methods evaluation Awarded by: Alcohol and Drug Foundation Funding Scheme: Information Services and Support (Family and Friends) Grant Program
2020 - 2022	Methamphetamine and mutual support: A mixed methods exploration of SMART Recovery participants' characteristics and opportunities for enhanced referral pathways Awarded by: National Centre for Clinical Research on Emerging Drugs (NCCRED) Funding Scheme: Seed Funding
2021	Evaluation of video-based information for families and friends of people with alcohol and other drug use concerns Awarded by: Australian Drug Foundation Funding Scheme: Family and Friends Research Grant Program
2020	Assessing mental health in young people attending residential substance use treatment programs: trialling an online approach Awarded by: Community Mental Health, Drug & Alcohol Research Network (CMHDARN) Funding Scheme: Innovation and Evaluation Grant
	BeSMART: feasibility and preliminary efficacy of an intervention for family members impacted by methamphetamine Awarded by: National Centre for Clinical Research on Emerging Drugs (NCCRED) Funding Scheme: Seed Funding
	Increasing the capacity of a local health district to respond to methamphetamine-related harm: developing an integrated model of care informed by linked data and consumer and clinician views Awarded by: National Centre for Clinical Research on Emerging Drugs (NCCRED) Funding Scheme: Seed Funding

Other Research Activities

• Farrell, M., Larance, B., Degenhardt, L., Nielsen, S., Shanahan, M., Dunlop, A., Lintzeris, N., Ali, R., Grebely, J., Treloar, C., Dore, G. (2018) Implementation trial of long-acting buprenorphine in community-based treatment settings (CoLAB). Collaborative research grant from Indivior ($1,814,558). 2018 - 2021
• Degenhardt, L., Blyth, F., Mattick, R., Shanahan, M., Cohen, M., Lintzeris, N., Bruno, R., Nielsen, S., Dobbins, T., Larance, B. Pharmaceutical opioids for chronic non-cancer pain: Evaluating health outcomes and economic impact over five years ($775,922, NHMRC Project Grant #1100822) 2016 - 2019

Impact Story

Potential Supervision Topics

• • Substance use disorders and treatment
  • Opioid dependence
  • Mental health and substance use
  • Physical health and substance use
  • Substance use and multicultural health
  Dr Larance is available to supervise Masters and PhD projects.

Advisees

• Graduate Advising Relationship

  Degree	Research Title	Advisee
  Doctor of Philosophy (Clinical Psychology)	Developing effective parenting programs for vulnerable families: Exploring the utility of a proposed theoretical framework	Osborne, Briony
  Doctor of Philosophy (Clinical Psychology)	Integrated Treatment for the Comorbid Presentation of Bipolar Disorder and Substance Use Disorder: Introducing Recovery Stories	Carradus, Lenna
  Doctor of Philosophy (Clinical Psychology)	Young people’s engagement and experiences with alcohol and other drug (AOD) treatment services	Wells, Megan
  Doctor of Philosophy	Treatment Trajectories in Residential Substance Dependence Treatment.	Hatton, Emma
  Doctor of Philosophy (Clinical Psychology)	Adverse childhood experiences and their association with risky substance use behaviours in adulthood: Identifying opportunities for intervention.	Tan, Kate

Professional Service Activities

• Illawarra Shoalhaven Local Health District Drug and Alcohol Services Research and Quality Committee Member 2019 -
• SMART Recovery Australia Research Advisory Committee Member 2018 -
• Drug and Alcohol Multicultural Education Centre (DAMEC) Board of Management Chairperson 2017 -

Awards And Honors

• Vice-Chancellor’s Research Excellence Award For Emerging Researcher, conferred by Vice Chancellor University of Wollongong , 2019
• Early Career Researcher Award, conferred by Australasian Professional Society of Alcohol and other Drugs , 2017
• Dean's Award for Academic Staff (Research Excellence), conferred by Faculty of Medicine, University of New South Wales, 2016
• Dean's List Award for PhD Students, conferred by Faculty of Medicine, University of New South Wales, 2010

Keywords

• opioids; heroin; opioid dependence; substance use disorders; methamphetamine; abuse deterrent formulations; anabolic steroids; performance and image enhancing drugs; people who inject drugs; methadone; buprenorphine; medication assisted treatment; help-seeking; alcohol and other drugs treatment

Mailing Address

• Room 128a, Building 41

  Northfields Avenue

  Wollongong

  NSW

  2522

  Australia

Orcid Id

• http://orcid.org/0000-0003-3800-7673 (confirmed)

Scopus Id

• 24477825300

Research Areas

• 110319 - PSYCHIATRY (INCL. PSYCHOTHERAPY)
• 1117 - PUBLIC HEALTH AND HEALTH SERVICES
• 111706 - EPIDEMIOLOGY
• 111708 - HEALTH AND COMMUNITY SERVICES
• 111711 - HEALTH INFORMATION SYSTEMS (INCL. SURVEILLANCE)
• 111714 - MENTAL HEALTH
• 170101 - BIOLOGICAL PSYCHOLOGY (NEUROPSYCHOLOGY, PSYCHOPHARMACOLOGY, PHYSIOLOGICAL PSYCHOLOGY)
• 170106 - HEALTH, CLINICAL AND COUNSELLING PSYCHOLOGY

Research Overview

• Dr Larance’s research examines strategies to reduce illicit drug harms and promote engagement with effective treatments for substance use disorders. Specific research interests include the use and extra-medical use of pharmaceutical opioids, 'abuse-deterrent' formulations, opioid dependence, anabolic steroids and methamphetamine. Her current projects include: a prospective cohort study of people prescribed opioids for non-cancer pain; a trial of long-acting (depot) buprenorphine injections for opioid dependence; a study examining opioid use among the Iranian community in Sydney; a feasibility trial of an app incorporating routine outcome monitoring and tailored feedback into mutual support groups (SMART Track); a study characterising SMART Recovery participants who use methamphetamine; studies examining suicide prevention responses in AOD services; a preliminary efficacy trial of an intervention for family and friends affected by someone else's methamphetamine use; and a mixed-methods study to increase the capacity of a Local Health District to respond to methamphetamine-related harm.

Head Of

• Board of Management, Drug and Alcohol Multicultural Education Centre Chairperson 2018 -

Member Of

• APSAD Conference Scientific Programming Committee 2020 -
• ISLHD Drug and Alcohol Research Committee 2018 -
• SMART Recovery Australia Research Advisory Committee 2018 -

Selected Publications

• Journal Article

  Year	Title
  2022	Economic analysis of out-of-pocket costs among people in opioid agonist treatment: A cross-sectional survey in three Australian jurisdictions Published In International Journal of Drug Policy
  2022	Examining the cost and impact of dosing fees among clients in opioid agonist treatment: Results from a cross-sectional survey of Australian treatment clients Published In Drug and Alcohol Review
  2022	Outcomes of a single-arm implementation trial of extended-release subcutaneous buprenorphine depot injections in people with opioid dependence Published In International Journal of Drug Policy
  2022	Self-reported challenges obtaining ongoing prescription opioids among Australians with chronic non-cancer pain Published In International Journal of Drug Policy
  2021	Characteristics and circumstances of death related to buprenorphine toxicity in Australia Published In Drug and Alcohol Dependence
  2021	Clinical correlates and outcomes associated with pregabalin use among people prescribed opioids for chronic non-cancer pain: A five-year prospective cohort study Published In British Journal of Clinical Pharmacology
  2021	Eating Disorder Behaviours and Substance Use in Women Attending Treatment for Substance Use Disorders: a Latent Class Analysis Published In International Journal of Mental Health and Addiction
  2021	Facilitators and barriers to integrating physical health care during treatment for substance use: A socio-ecological analysis Published In Drug and Alcohol Review
  2021	Feasibility of a mobile health app for routine outcome monitoring and feedback in SMART recovery mutual support groups: Stage 1 mixed methods pilot study Published In Journal of Medical Internet Research
  2021	Perceptions of injectable opioid agonist treatment (iOAT) among people who regularly use opioids in Australia: findings from a cross-sectional study in three Australian cities Published In Addiction
  2021	Pharmaceutical Opioid Use Patterns and Indicators of Extramedical Use and Harm in Adults with Chronic Noncancer Pain, 2012-2018 Published In JAMA Network Open
  2021	Preliminary psychometric evaluation of the patient reported experience measure for addiction treatment (PREMAT) Published In Addictive Behaviors
  2021	Routine outcome measurement in specialist non-government alcohol and other drug treatment services: Establishing effectiveness indicators for the NADAbase Published In Drug and Alcohol Review
  2021	SMART Recovery International and COVID-19: Expanding the reach of mutual support through online groups Published In Journal of Substance Abuse Treatment
  2021	The use of Australian SMART Recovery groups by people who use methamphetamine: Analysis of routinely-collected nationwide data Published In Drug and Alcohol Dependence
  2020	A population-based study of transdermal fentanyl initiation in Australian clinical practice Published In European Journal of Clinical Pharmacology
  2020	A protocol for a discrete choice experiment: Understanding patient medicine preferences for managing chronic non-cancer pain Published In BMJ Open
  2020	Antidepressant Use Among People Prescribed Opioids for Chronic Noncancer Pain Published In Pain Medicine
  2020	Circumstances of death of opioid users being treated with naltrexone Published In Addiction
  2020	Concerns and Help-Seeking Among Patients Using Opioids for Management of Chronic Noncancer Pain Published In Pain Medicine
  2020	Effectiveness and framing of pharmaceutical opioid abuse-deterrent formulations Published In Addiction
  2020	Health care engagement behaviors of men who use performance- and image-enhancing drugs in Australia Published In Substance Abuse
  2020	Increases in controlled-release oxycodone utilisation following the subsidy of oxycodone with naloxone formulations: An Australian population-based study Published In Pharmacoepidemiology and Drug Safety
  2020	Post‐marketing studies of pharmaceutical opioid abuse‐deterrent formulations: a framework for research design and reporting Published In Addiction
  2020	Regulatory and other responses to the pharmaceutical opioid problem Published In Medical Journal of Australia
  2020	Regulatory and other responses to the pharmaceutical opioid problem Published In Medical Journal of Australia
  2020	Trends in methamphetamine and opioid use among clients of needle-syringe programs in Queensland, Australia: 2007–2015 Published In Drug and Alcohol Review
  2020	Correlates of indicators of potential extra-medical opioid use in people prescribed opioids for chronic non-cancer pain Published In Drug and Alcohol Review
  2020	Development of a brief patient-administered screening tool for prescription opioid dependence for primary care settings Published In Pain Medicine (United States)
  2020	Feasibility of a mobile health app for routine outcome monitoring and feedback in mutual support groups coordinated by SMART recovery Australia: Protocol for a pilot study Published In JMIR Research Protocols
  2020	Open-label, multicentre, single-arm trial of monthly injections of depot buprenorphine in people with opioid dependence: Protocol for the CoLAB study Published In BMJ Open
  2020	Opioid use and harms associated with a sustained-release tapentadol formulation: A post-marketing surveillance study Published In Drug and Alcohol Dependence
  2020	Perceptions of extended-release buprenorphine injections for opioid use disorder among people who regularly use opioids in Australia Published In Addiction
  2020	Risk factors for indicators of opioid-related harms amongst people living with chronic non-cancer pain: Findings from a 5-year prospective cohort study Published In EClinicalMedicine
  2020	Substance Use and Co-occurring Physical Health Problems: File Review of a Residential Drug and Alcohol Treatment Service Published In Journal of Dual Diagnosis
  2019	A population-based study of transdermal fentanyl initiation in Australian clinical practice Published In European Journal of Clinical Pharmacology
  2019	A protocol for a discrete choice experiment: Understanding patient medicine preferences for managing chronic non-cancer pain Published In BMJ Open
  2019	Antidepressant Use Among People Prescribed Opioids for Chronic Noncancer Pain Published In Pain Medicine
  2019	Circumstances of death of opioid users being treated with naltrexone Published In Addiction
  2019	Concerns and Help-Seeking Among Patients Using Opioids for Management of Chronic Noncancer Pain Published In Pain Medicine
  2019	Effectiveness and framing of pharmaceutical opioid abuse-deterrent formulations Published In Addiction
  2019	Health care engagement behaviors of men who use performance- and image-enhancing drugs in Australia Published In Substance Abuse
  2019	Increases in controlled-release oxycodone utilisation following the subsidy of oxycodone with naloxone formulations: An Australian population-based study Published In Pharmacoepidemiology and Drug Safety
  2019	Post‐marketing studies of pharmaceutical opioid abuse‐deterrent formulations: a framework for research design and reporting Published In Addiction
  2019	Regulatory and other responses to the pharmaceutical opioid problem Published In Medical Journal of Australia
  2019	Regulatory and other responses to the pharmaceutical opioid problem Published In Medical Journal of Australia
  2019	Trends in methamphetamine and opioid use among clients of needle-syringe programs in Queensland, Australia: 2007–2015 Published In Drug and Alcohol Review
  2018	A nationwide study of the extent and factors associated with fentanyl use in Australia Published In Research in Social and Administrative Pharmacy
  2018	Alcohol use disorder and associated physical health complications and treatment amongst individuals with and without opioid dependence: A case-control study Published In Drug and Alcohol Dependence
  2018	Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study Published In The Lancet Public Health
  2018	Knowledge of Opioid Overdose and Attitudes to Supply of Take-Home Naloxone Among People with Chronic Noncancer Pain Prescribed Opioids Published In Pain Medicine
  2018	Opioid use and harms associated with a sustained-release tapentadol formulation: a postmarketing study protocol Published In BMJ Open
  2018	Perceived stigma and social support in treatment for pharmaceutical opioid dependence Published In Drug and Alcohol Review
  2018	Person-level changes in oxycodone use after the introduction of a tamper-resistant formulation in Australia Published In CMAJ
  2018	Pharmaceutical opioid use and harm in Australia: The need for proactive and preventative responses Published In Drug and Alcohol Review
  2018	Physical appearance concerns are uniquely associated with the severity of steroid dependence and depression in anabolic–androgenic steroid users Published In Drug and Alcohol Review
  2018	Predictors of transitions across stages of heroin use and dependence prior to treatment-seeking among people in treatment for opioid dependence Published In Drug and Alcohol Dependence
  2018	Prescription Opioid Access Patterns and Factors Associated with Increasing Number of Prescribers, Pharmacies, and Dispensings: An Observational Study Using Pharmaceutical Claims Published In Pain Medicine
  2018	The effect of a potentially tamper-resistant oxycodone formulation on opioid use and harm: main findings of the National Opioid Medications Abuse Deterrence (NOMAD) study Published In The Lancet Psychiatry
  2018	To what extent do data from pharmaceutical claims under‐estimate opioid analgesic utilisation in Australia? Published In Pharmacoepidemiology and Drug Safety
  2018	Understanding an emerging treatment population: Protocol for and baseline characteristics of a prospective cohort of people receiving treatment for pharmaceutical opioid dependence Published In Drug and Alcohol Review
  2017	A systematic review of opioid agonist treatments for pharmaceutical opioid dependence Published In Drug and Alcohol Dependence
  2017	Defined daily doses (DDD) do not accurately reflect opioid doses used in contemporary chronic pain treatment Published In Pharmacoepidemiology and Drug Safety
  2017	Defining problematic pharmaceutical opioid use among people prescribed opioids for chronic non-cancer pain: Different measures, same patients? Published In Drug and Alcohol Dependence
  2017	Opioid Agonist Treatment for Patients With Dependence on Prescription Opioids Published In JAMA: Journal of the American Medical Association
  2017	Protecting Pain Patients. The Evaluation of a Chronic Pain Educational Intervention Published In Pain Medicine
  2017	Same-day use of opioids and depressants: A retrospective diary study Published In Drug and Alcohol Dependence
  2017	Trends in PIEDs use among male clients of needle–syringe programs in Queensland, Australia; 2007–2015 Published In International Journal of Drug Policy
  2016	A Typology of Predictive Risk Factors for Non-Adherent Medication-Related Behaviors among Chronic Non-Cancer Pain Patients Prescribed Opioids: A Cohort Study Published In Pain Physician
  2016	A cross‐sectional study of correlates of imprisonment in opioid‐dependent men and women in New South Wales, Australia Published In Drug and Alcohol Review
  2016	Alprazolam use and related harm among opioid substitution treatment clients – 12 months follow up after regulatory rescheduling Published In International Journal of Drug Policy
  2016	An ecological study of the extent and factors associated with the use of prescription and over-the-counter codeine in Australia Published In European Journal of Clinical Pharmacology
  2016	Defining problematic pharmaceutical opioid use among people prescribed opioids for chronic noncancer pain: do different measures identify the same patients? Published In Pain
  2016	Development of a brief tool for monitoring aberrant behaviours among patients receiving long-term opioid therapy: The Opioid-Related Behaviours In Treatment (ORBIT) scale Published In Drug and Alcohol Dependence
  2016	Diversion and injection of buprenorphine–naloxone film two years post‐introduction in Australia Published In Drug and Alcohol Review
  2016	Geographic Variation in Health Service Use and Perceived Access Barriers for Australian Adults with Chronic Non-Cancer Pain Receiving Opioid Therapy Published In Pain Medicine
  2016	Initiation of strong prescription opioids in Australia: cohort characteristics and factors associated with the type of opioid initiated Published In British Journal of Clinical Pharmacology
  2016	Opioid agonist treatment for pharmaceutical opioid dependent people (Review) Published In Cochrane Database of Systematic Reviews
  2016	Pain, alcohol use disorders and risky patterns of drinking among people with chronic non-cancer pain receiving long-term opioid therapy Published In Drug and Alcohol Dependence
  2016	Same-day use of opioids and other central nervous system depressants amongst people who tamper with pharmaceutical opioids: A retrospective 7-day diary study Published In Drug and Alcohol Dependence
  2016	Sleep Quality Among People Living With Chronic Noncancer Pain: Findings From the Pain and Opioids IN Treatment (POINT) Cohort Published In Clinical Journal of Pain
  2016	The extent and correlates of community‐based pharmaceutical opioid utilisation in Australia Published In Pharmacoepidemiology and Drug Safety
  2016	The extramedical use and diversion of opioid substitution medications and other medications in prison settings in Australia following the introduction of buprenorphine–naloxone film Published In Drug and Alcohol Review
  2015	A longitudinal comparison of retention in buprenorphine and methadone treatment for opioid dependence in New South Wales, Australia Published In Addiction
  2015	A typology of people who tamper with pharmaceutical opioids: responses to introduction of a tamper‐resistant formulation of controlled‐release oxycodone Published In Pharmacoepidemiology and Drug Safety
  2015	Agreement between definitions of pharmaceutical opioid use disorders and dependence in people taking opioids for chronic non-cancer pain (POINT): a cohort study Published In The Lancet Psychiatry
  2015	Benzodiazepine Use among Chronic Pain Patients Prescribed Opioids: Associations with Pain, Physical and Mental Health, and Health Service Utilization Published In Pain Medicine
  2015	Benzodiazepine use among a sample of chronic pain patients prescribed opioids Published In Drug and Alcohol Dependence
  2015	Evaluating the potential impact of a reformulated version of oxycodone upon tampering, non‐adherence and diversion of opioids: the National Opioid Medications Abuse Deterrence (NOMAD) study protocol Published In Addiction
  2015	Factors associated with the development of depression in chronic non-cancer pain patients following the onset of opioid treatment for pain Published In Journal of Affective Disorders
  2015	Injecting buprenorphine‐naloxone film: Findings from an explorative qualitative study Published In Drug and Alcohol Review
  2015	Jurisdictional differences in opioid use, other licit and illicit drug use, and harms associated with substance use among people who tamper with pharmaceutical opioids Published In Drug and Alcohol Review
  2015	Methods and predictors of tampering with a tamper-resistant controlled-release oxycodone formulation Published In International Journal of Drug Policy
  2015	Opioid therapy for chronic non-cancer pain: Does typology of risk predict aberrant behaviour? Published In Drug and Alcohol Dependence
  2015	Pharmaceutical Opioid Use and Dependence among People Living with Chronic Pain: Associations Observed within the Pain and Opioids in Treatment (POINT) Cohort Published In Pain Medicine
  2015	Pharmaceutical opioid use and dependence among people living with chronic pain: Associations observed within the pain and opioids in treatment cohort Published In Drug and Alcohol Dependence
  2015	Reducing extramedical use and harms of pharmaceutical opioids: the potential role of abuse-deterrent formulations Published In The Lancet Psychiatry
  2015	Sex differences in alcohol use disorders and risky drinking among chronic non-cancer pain patients receiving opioid therapy Published In Drug and Alcohol Dependence
  2015	The POPPY Research Programme protocol: investigating opioid utilisation, costs and patterns of extramedical use in Australia Published In BMJ Open
  2015	The Pain and Opioids IN Treatment study: characteristics of a cohort using opioids to manage chronic non-cancer pain Published In Pain
  2015	The characteristics of a cohort who tamper with prescribed and diverted opioid medications Published In Journal of Substance Abuse Treatment
  2015	The introduction of a potentially abuse deterrent oxycodone formulation: Early findings from the Australian National Opioid Medications Abuse Deterrence (NOMAD) study Published In Drug and Alcohol Dependence
  2015	The introduction of buprenorphine‐naloxone film in opioid substitution therapy in Australia: Uptake and issues arising from changing buprenorphine formulations Published In Drug and Alcohol Review
  2015	The use of paracetamol (acetaminophen) among a community sample of people with chronic non‐cancer pain prescribed opioids Published In International Journal of Clinical Practice
  2015	Xamining DSM and ICD definitions of pharmaceutical opioid dependence in people taking opioids for chronic pain: Findings from the pain and opioids in treatment study Published In Drug and Alcohol Dependence
  2014	A comparative study of opioid substitution therapy utilisation among opioid‐dependent men and women Published In Drug and Alcohol Review
  2014	A latent class analysis of self-reported clinical indicators of psychosocial stability and adherence among opioid substitution therapy patients: Do stable patients receive more unsupervised doses? Published In Drug and Alcohol Dependence
  2014	Australian post-marketing surveillance studies, 2012 Published In Drug and Alcohol Dependence
  2014	Cohort protocol paper: The Pain and Opioids In Treatment (POINT) study Published In BMC Pharmacology and Toxicology
  2014	Diversion of prescribed opioids by people living with chronic pain: Results from an Australian community sample Published In Drug and Alcohol Review
  2014	Is pain associated with illicit opioid use or aberrant opioid-related behaviors in opioid substitution treatment patients Published In Drug and Alcohol Dependence
  2014	Opioid agonist treatment for pharmaceutical opioid dependent people (Protocol) Published In Cochrane Database of Systematic Reviews
  2014	The diversion and injection of a buprenorphine-naloxone soluble film formulation Published In Drug and Alcohol Dependence
  2013	A randomised controlled trial of sublingual buprenorphine–naloxone film versus tablets in the management of opioid dependence Published In Drug and Alcohol Dependence
  2013	Correlates of pain in an in‐treatment sample of opioid‐dependent people Published In Drug and Alcohol Review
  2013	Estimating the proportion of prescription opioids that is consumed by people who inject drugs in Australia Published In Drug and Alcohol Review
  2011	Definitions related to the use of pharmaceutical opioids: Extramedical use, diversion, non-adherence and aberrant medication-related behaviours Published In Drug and Alcohol Review
  2011	Post-marketing surveillance of buprenorphine-naloxone in Australia: Diversion, injection and adherence with supervised dosing Published In Drug and Alcohol Dependence
  2011	Prescribers' perceptions of the diversion and injection of medication by opioid substitution treatment patients Published In Drug and Alcohol Review
  2011	Prescription of opioid analgesics and related harms in Australia Published In Medical Journal of Australia
  2011	The availability, diversion and injection of pharmaceutical opioids in South Asia Published In Drug and Alcohol Review
  2011	The prevalence and correlates of buprenorphine inhalation amongst opioid substitution treatment (OST) clients in Australia Published In International Journal of Drug Policy
  2009	Injection of medications used in opioid substitution treatment in Australia after the introduction of a mixed partial agonist-antagonist formulation Published In Medical Journal of Australia
  2008	Drug dependence and associated risks among female street-based sex workers in the greater Sydney area, Australia Published In Substance Use and Misuse
  2008	Injecting risk behaviour and related harm among men who use performance- and image-enhancing drugs Published In Drug and Alcohol Review

• Chapter

  Year	Title
  2020	Opioids Published In New Oxford Textbook of Psychiatry Publisher Oxford University Press

• Conference Paper

  Year	Title
  2020	Drawing on regional data analytics and stakeholder consultation to improve responses to methamphetamine-related harm in a New South Wales Local Health District Published In National Centre for Clinical Research on Emerging Drugs Inaugural Symposium
  2019	Drawing on regional data analytics and stakeholder consultation to improve responses to methamphetamine-related harm in a New South Wales Local Health District Published In National Centre for Clinical Research on Emerging Drugs Inaugural Symposium

• Other Publications

  Year	Title
  2015	Understanding the health and service needs of diverse populations of pharmaceutical opioid users: Cohort studies of dependent users in treatment, and people who inject drugs

Investigator On

Year	Title
2021 - 2022	Building peer and provider capacity to effectively deliver SMART Family and friends meetings: A two stage mixed methods evaluation Awarded by: Alcohol and Drug Foundation Funding Scheme: Information Services and Support (Family and Friends) Grant Program
2020 - 2022	Methamphetamine and mutual support: A mixed methods exploration of SMART Recovery participants' characteristics and opportunities for enhanced referral pathways Awarded by: National Centre for Clinical Research on Emerging Drugs (NCCRED) Funding Scheme: Seed Funding
2021	Evaluation of video-based information for families and friends of people with alcohol and other drug use concerns Awarded by: Australian Drug Foundation Funding Scheme: Family and Friends Research Grant Program
2020	Assessing mental health in young people attending residential substance use treatment programs: trialling an online approach Awarded by: Community Mental Health, Drug & Alcohol Research Network (CMHDARN) Funding Scheme: Innovation and Evaluation Grant
	BeSMART: feasibility and preliminary efficacy of an intervention for family members impacted by methamphetamine Awarded by: National Centre for Clinical Research on Emerging Drugs (NCCRED) Funding Scheme: Seed Funding
	Increasing the capacity of a local health district to respond to methamphetamine-related harm: developing an integrated model of care informed by linked data and consumer and clinician views Awarded by: National Centre for Clinical Research on Emerging Drugs (NCCRED) Funding Scheme: Seed Funding

Other Research Activities

• Farrell, M., Larance, B., Degenhardt, L., Nielsen, S., Shanahan, M., Dunlop, A., Lintzeris, N., Ali, R., Grebely, J., Treloar, C., Dore, G. (2018) Implementation trial of long-acting buprenorphine in community-based treatment settings (CoLAB). Collaborative research grant from Indivior ($1,814,558). 2018 - 2021
• Degenhardt, L., Blyth, F., Mattick, R., Shanahan, M., Cohen, M., Lintzeris, N., Bruno, R., Nielsen, S., Dobbins, T., Larance, B. Pharmaceutical opioids for chronic non-cancer pain: Evaluating health outcomes and economic impact over five years ($775,922, NHMRC Project Grant #1100822) 2016 - 2019

Impact Story

Potential Supervision Topics

• • Substance use disorders and treatment
  • Opioid dependence
  • Mental health and substance use
  • Physical health and substance use
  • Substance use and multicultural health
  Dr Larance is available to supervise Masters and PhD projects.

Advisees

• Graduate Advising Relationship

  Degree	Research Title	Advisee
  Doctor of Philosophy (Clinical Psychology)	Developing effective parenting programs for vulnerable families: Exploring the utility of a proposed theoretical framework	Osborne, Briony
  Doctor of Philosophy (Clinical Psychology)	Integrated Treatment for the Comorbid Presentation of Bipolar Disorder and Substance Use Disorder: Introducing Recovery Stories	Carradus, Lenna
  Doctor of Philosophy (Clinical Psychology)	Young people’s engagement and experiences with alcohol and other drug (AOD) treatment services	Wells, Megan
  Doctor of Philosophy	Treatment Trajectories in Residential Substance Dependence Treatment.	Hatton, Emma
  Doctor of Philosophy (Clinical Psychology)	Adverse childhood experiences and their association with risky substance use behaviours in adulthood: Identifying opportunities for intervention.	Tan, Kate

Professional Service Activities

• Illawarra Shoalhaven Local Health District Drug and Alcohol Services Research and Quality Committee Member 2019 -
• SMART Recovery Australia Research Advisory Committee Member 2018 -
• Drug and Alcohol Multicultural Education Centre (DAMEC) Board of Management Chairperson 2017 -

Awards And Honors

• Vice-Chancellor’s Research Excellence Award For Emerging Researcher, conferred by Vice Chancellor University of Wollongong , 2019
• Early Career Researcher Award, conferred by Australasian Professional Society of Alcohol and other Drugs , 2017
• Dean's Award for Academic Staff (Research Excellence), conferred by Faculty of Medicine, University of New South Wales, 2016
• Dean's List Award for PhD Students, conferred by Faculty of Medicine, University of New South Wales, 2010

Keywords

• opioids; heroin; opioid dependence; substance use disorders; methamphetamine; abuse deterrent formulations; anabolic steroids; performance and image enhancing drugs; people who inject drugs; methadone; buprenorphine; medication assisted treatment; help-seeking; alcohol and other drugs treatment

Mailing Address

• Room 128a, Building 41

  Northfields Avenue

  Wollongong

  NSW

  2522

  Australia

Orcid Id

• http://orcid.org/0000-0003-3800-7673 (confirmed)

Scopus Id

• 24477825300