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van Oijen, Antoine M. Distinguished Professor

Director Molecular Horizons

  • Faculty of Science, Medicine and Health
  • School of Chemistry & Molecular Bioscience
  • Leadership Fellow - National Health and Medical Research Council (NHMRC) 2021 - 2025

Top Publications


Research Overview


  • Antoine van Oijen obtained his BSc and PhD degrees in the Netherlands, where he was trained as a physicist.  A growing fascination for biology resulted in him moving to the USA and establishing a research group at Harvard Medical School. Subsequently, he was appointed as full professor at Groningen University in the Netherlands where he established a thriving biophysics research program focused on the development of single-molecule visualisation techniques and their applications in basic and applied science. In 2014, he moved to the UOW and was awarded a prestigious Laureate Fellowship by the Australian Research Council to further develop biophysical approaches to visualise the molecular processes that define life. He is currently Director of Molecular Horizons and an NHMRC Leadership Fellow.

Selected Publications


Investigator On


Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Functional Implications of RarA at the Escherichia Coli Replication Fork
    Doctor of Philosophy Single-molecule studies of Saccharomyces cerevisiae DNA replication Natarajan, Varsha
    Doctor of Philosophy Studying the Chaperone Function of Small Heat-Shock Proteins Using Single-Molecule Fluorescence Microscopy Johnston, Caitlin
    Doctor of Philosophy The role of translesion DNA synthesis in the development of antibiotic resistance Cherry, Megan
    Doctor of Philosophy The Development of Single-Molecule Approaches to Study Molecular Chaperone Function Marzano, Nicholas
    Doctor of Philosophy Exploring Helicase Dynamics in Bacterial DNA Replication: A Single-Molecule Approach Spinks, Richard
    Doctor of Philosophy Single-molecule studies of the bacterial replisome Mueller, Stefan
    Doctor of Philosophy Visualising Single-Strand Gap Repair in Live Escherichia Coli Cells Armstrong, Thomas
    Doctor of Philosophy Dynamic Iinteractions of E. coli Accessory Helicases Rep and UvrD with Stalled Replication Forks Whinn, Kelsey
    Doctor of Philosophy Antibiotic-induced evolution: combining microscopy, microfluidics and genomics to study resistance in individual bacterial cells Ripandelli, Remy
    Doctor of Philosophy Roles of Bacterial DNA Repair Pathways in Antibiotic Resistance Wright, Elizabeth
    Doctor of Philosophy Developing Single-Molecule Approaches to Investigate Interactions Between Alpha-Synuclein and Heat Shock Protein Molecular Chaperones Rice, Lauren
    Doctor of Philosophy Single-molecule Imaging Analysis of Postreplicative Gap Formation and Repair in Escherichia coli Belhaffef, Ouraida Amira
    Doctor of Philosophy Conquering chronic pain: an investigation into the structural and functional effects of the a-conotoxin Vc1.1 on GABA(B) receptor mediated G-protein signalling. Steele, Maddie
    Doctor of Philosophy Investigating the role of recombination mediator proteins in the formation and resolution of single-strand gaps during the E. coli DNA damage response using single molecule live cell imaging. Studying replication-transcription conflicts at the singl... Sharma, Nischal

Top Publications


Research Overview


  • Antoine van Oijen obtained his BSc and PhD degrees in the Netherlands, where he was trained as a physicist.  A growing fascination for biology resulted in him moving to the USA and establishing a research group at Harvard Medical School. Subsequently, he was appointed as full professor at Groningen University in the Netherlands where he established a thriving biophysics research program focused on the development of single-molecule visualisation techniques and their applications in basic and applied science. In 2014, he moved to the UOW and was awarded a prestigious Laureate Fellowship by the Australian Research Council to further develop biophysical approaches to visualise the molecular processes that define life. He is currently Director of Molecular Horizons and an NHMRC Leadership Fellow.

Selected Publications


Investigator On


Advisees


  • Graduate Advising Relationship

    Degree Research Title Advisee
    Doctor of Philosophy Functional Implications of RarA at the Escherichia Coli Replication Fork
    Doctor of Philosophy Single-molecule studies of Saccharomyces cerevisiae DNA replication Natarajan, Varsha
    Doctor of Philosophy Studying the Chaperone Function of Small Heat-Shock Proteins Using Single-Molecule Fluorescence Microscopy Johnston, Caitlin
    Doctor of Philosophy The role of translesion DNA synthesis in the development of antibiotic resistance Cherry, Megan
    Doctor of Philosophy The Development of Single-Molecule Approaches to Study Molecular Chaperone Function Marzano, Nicholas
    Doctor of Philosophy Exploring Helicase Dynamics in Bacterial DNA Replication: A Single-Molecule Approach Spinks, Richard
    Doctor of Philosophy Single-molecule studies of the bacterial replisome Mueller, Stefan
    Doctor of Philosophy Visualising Single-Strand Gap Repair in Live Escherichia Coli Cells Armstrong, Thomas
    Doctor of Philosophy Dynamic Iinteractions of E. coli Accessory Helicases Rep and UvrD with Stalled Replication Forks Whinn, Kelsey
    Doctor of Philosophy Antibiotic-induced evolution: combining microscopy, microfluidics and genomics to study resistance in individual bacterial cells Ripandelli, Remy
    Doctor of Philosophy Roles of Bacterial DNA Repair Pathways in Antibiotic Resistance Wright, Elizabeth
    Doctor of Philosophy Developing Single-Molecule Approaches to Investigate Interactions Between Alpha-Synuclein and Heat Shock Protein Molecular Chaperones Rice, Lauren
    Doctor of Philosophy Single-molecule Imaging Analysis of Postreplicative Gap Formation and Repair in Escherichia coli Belhaffef, Ouraida Amira
    Doctor of Philosophy Conquering chronic pain: an investigation into the structural and functional effects of the a-conotoxin Vc1.1 on GABA(B) receptor mediated G-protein signalling. Steele, Maddie
    Doctor of Philosophy Investigating the role of recombination mediator proteins in the formation and resolution of single-strand gaps during the E. coli DNA damage response using single molecule live cell imaging. Studying replication-transcription conflicts at the singl... Sharma, Nischal
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